Sex Differences in the Brain: From Genes to Behavior

Hardcover | November 20, 2007

EditorJill B. Becker, Karen J. Berkley, Nori Geary

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Sex is a fundamentally important biological variable. Recent years have seen significant progress in the integration of sex in many aspects of basic and clinical research, including analyses of sex differences in brain function. Significant advances in the technology available for studyingthe endocrine and nervous systems are now coupled with a more sophisticated awareness of the interconnections of these two communication systems of the body. A thorough understanding of the current knowledge, conceptual approaches, methodological capabilities, and challenges is a prerequisite tocontinued progress in research and therapeutics in this interdisciplinary area. Sex Differences in the Brain provides scientists with the basic tools for investigating sex differences in brain and behavior and insight into areas where important progress in understanding physiologically relevant sex differences has already been made. The book is arranged in three parts. Thefirst part of the book introduces the study of sex differences in the brain, with an overview of how the brain, stress systems, and pharmacogenomics differ in males and females and how this information is important for the study of behavior and neurobiology of both genders. The second part presentsexamples of sex differences in neurobiology and behavior from both basic and clinical research perspectives, covering both humans and nonhuman animals. The final part discusses sex differences in the neurobiology of disease and neurological disorders. For interested individuals as well as those who are considering conducting research at the intersections of endocrinology, neuroscience, and other areas of biomedicine, the study of sex differences offers exciting and challenging questions and perspectives. This book is intended as a guide andresource for clinicians, scientists, and students.

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From the Publisher

Sex is a fundamentally important biological variable. Recent years have seen significant progress in the integration of sex in many aspects of basic and clinical research, including analyses of sex differences in brain function. Significant advances in the technology available for studyingthe endocrine and nervous systems are now coup...

Jill Becker is a Professor of Psychology at the University of Michigan. Karen Berkley is McKenzie Professor of Psychology and Neuroscience at Florida State University in Tallahasee. Nori Geary is a Professor at the Institute of Animal Science at the Swiss Federal Institute of Technology in Zurich. James Herman is a Professor of Psychi...

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Format:HardcoverDimensions:608 pages, 7.2 × 10 × 0.91 inPublished:November 20, 2007Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195311582

ISBN - 13:9780195311587

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Table of Contents

PrefaceForeword (Thomas R. Insel, M.D.)Foreword (Sherry A. Marts, Ph.D.)Part One: Strategies, Methods and Background1. Why are There Two Sexes?2. Sex Differences in the Brain: What's Old and What's New?3. Research and Methodological Issues in the Study of Sex Differences and Hormone-Behavior4. Methodological Issues in the Study of Hormone-Behavior Relations in Humans: Understanding and Monitoring the Menstrual Cycle5. Sex Differences in Pharmacogenomics as a Tool to Study CNS Disorders6. Sex Differences in HPA Axis RegulationPart Two: Sex Differences in Neurobiology and Behavior7. Steroid Hormone Receptors and Sex Differences in Behavior8. Sex Differences Affiliative Behavior and Social Bonding9. Sex Differences in the Organization of Movement10. Sex Differences in Motivation11. Sex Differences in Neuroplasticity12. Sex Differences in Cogntiive Function in Rodents13. Sex Difference in Energy Metabolism, Obesity and Eating Behavior14. Sex Differences in Children's Play15. Sex Differences in the Neurocognition of Language16. Endocrine Contributions to Sex Differences in Visuospatial Perception and CognitionPart Three: Sex Differences in the Neurobiology of Disease17. Sex Differences in Infectious and Autoimmune Diseases18. Sex Differences in Neuroimmunology19. Sex Differences in Pain Syndromes20. Sex Differences in Anxiety Disorders21. Hormones and Mood22. Sex Differences in Brain Aging and Alzheimer's Disease23. Sex Differences in Parkinson's Disease

Editorial Reviews

"It is refreshing...to see authors discourse on the neurobiology of sex differences as a scientific rather than social entity. The book is quite informative on a number of topics."--Doody's "Doctor Becker and her five colleagues have written and edited a brilliant, long-overdue guidebook leading us to better understanding, treatment, and care of men and women...The questing student of any age will find answers to many thorny questions- as well as more challenges to his or her perspectives and relationships."--Nancy Yanes-Hoffman, from the Writing Doctor blog "Information content is high, references are ample, and the continuity between different chapters has been skillfully coordinated...These chapters deserve to be widely read, and they will undoubtedly attract bright young minds to the field."--Science "A worthwhile addition to any collection. Recommended."--Choice