Signal Transduction and the Coordination of B Lymphocyte Development and Function II: Translation of BCR Signals to Specific Physiologic Outcomes by Louis B. JustementSignal Transduction and the Coordination of B Lymphocyte Development and Function II: Translation of BCR Signals to Specific Physiologic Outcomes by Louis B. Justement

Signal Transduction and the Coordination of B Lymphocyte Development and Function II: Translation…

EditorLouis B. Justement, Katherine A. Siminovitch

Paperback | September 18, 2011

not yet rated|write a review

Pricing and Purchase Info

$294.04 online 
$336.95 list price save 12%
Earn 1470 plum® points

In stock online

Ships free on orders over $25

Not available in stores

about

This volume provides a review of current research in the field of B cell development and differentiation with particular emphasis on signal transduction processes. The volume is divided into two parts that focus, respectively, on the basic biochemical pathways which regulate B cell biology and the role of signal transduction processes in regulating various aspects of B cell function, development and differentiation. In this second part the molecular processes involved in translating BCR engagement to specific biological outcomes are reviewed. Topics covered in this part include signal transduction via the pre-B cell antigen receptor complex, the control of immunoglobulin gene recombination and allelic exclusion, and molecular regulation of positive and negative selection. These latter chapters present information regarding processes which are critical for the B cell response to foreign antigen that leads to differentiation into antibody secreting plasma.

Details & Specs

Title:Signal Transduction and the Coordination of B Lymphocyte Development and Function II: Translation…Format:PaperbackDimensions:187 pages, 9.25 × 6.1 × 0.68 inPublished:September 18, 2011Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642640648

ISBN - 13:9783642640643

Look for similar items by category:

Customer Reviews of Signal Transduction and the Coordination of B Lymphocyte Development and Function II: Translation of BCR Signals to Specific Physiologic Outcomes

Reviews

Extra Content

Table of Contents

B-Cell Antigen Receptor Signaling in Immature-Stage B Cells: Integrating Intrinsic and Extrinsic Signals.- Signaling Pathways that Control V(D)J Recombination.- B-Cell-Receptor-Dependent Positive and Negative Selection in Immature B Cell.- CD40-CD154 Interactions in B-Cell Signaling.- B-Lymphocyte Signaling Receptors and the Control of Class-II Antigen Processing.- Molecular Processes that Regulate Class Switching.