Signal Transduction

Other | September 22, 2009

byBastien D. Gomperts, Bastien D. Gomperts, Ijsbrand M. Kramer...

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Signal Transduction,2e,is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention.Signal Transduction,2e,serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.

  • Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention
  • In-depth coverage of nuclear receptors, including steps in isolation of steroid hormones and the discovery of intracellular hormone receptors; tyrosine protein kinases and adaptive immunity; and intracellular calcium
  • Extensive conceptual color artwork to assist with comprehension of key topics
  • Instrumental margin notes highlight milestones in signaling mechanisms

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From the Publisher

Signal Transduction,2e,is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive co...

Format:OtherDimensions:840 pages, 1 × 1 × 1 inPublished:September 22, 2009Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080919057

ISBN - 13:9780080919058

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Table of Contents

Chapter 1 Prologue: Signal Transduction, origins and ancestors
Chapter 2 First messengers
Chapter 3 Receptors
Chapter 4 GTP-binding proteins and signal transduction
Chapter 5 Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C
Chapter 6 The regulation of visual transduction and olfaction
Chapter 7 Intracellular calcium
Chapter 8 Calcium effectors
Chapter 9 Phosphorylation and dephosphorylation: protein kinases A and C
Chapter 10 Nuclear receptors
Chapter 11 Growth Factors: setting the framework
Chapter 12 Signalling pathways operated by receptor protein tyrosine kinases
Chapter 13 Signal transduction to and from adhesion molecules
Chapter 14 Adhesion molecules in the regulation of cell differentiation: Mainly about Wnt
Chapter 15 Activation of the innate immune system: the Toll-like receptor 4 and Signalling through Ubiquitylation
Chapter 16 Traffic of white blood cells
Chapter 17 Tyrosine protein kinases and adaptive immunity : TCR, BCR, soluble tyrosine kinases and NFAT
Chapter 18 Phosphoinositide 3 kinases, protein kinase B and signalling through the insulin receptor
Chapter 19 Protein Kinase C revisited
Chapter 20 Signalling through receptor serine/threonine kinases
Chapter 21 Protein dephosphorylation and protein phosphorylation
Chapter 22 Notch
Chapter 23 Targeting transduction pathways for research and medical intervention
Chapter 24 Protein domains and signal transduction