Single Cell Analysis in Biotechnology and Systems Biology by Fan-Gang TsengSingle Cell Analysis in Biotechnology and Systems Biology by Fan-Gang Tseng

Single Cell Analysis in Biotechnology and Systems Biology

EditorFan-Gang Tseng, Tuhin Subhra Santra

Hardcover | May 20, 2016

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Cells play significant roles in our day to day life. However, the interactions of cells, the cellular responses of organelles to molecules, and their intracellular behaviour, are still not fully understood. To better understand the physiological interactions among molecules, organelles, and cells, the ensemble measurement of (on average, millions of) cells cannot provide detailed information. However, for example, research concerning the differentiation behaviors of stem cells or the metastatic processes of tumour initiation requires detailed information. Understanding genomic sequence information at a single cell level can promote an understanding of how individual parts of a cell are integrated in time and space to form dynamic cellular processes. The relationship between cellular heterogeneity and signaling pathway regulation may result in an understanding of disease states that can potentially drive therapeutic interventions. Thus single cell analysis (SCA) has been emerging as a powerful method of investigating exciting new insights into genomics, fluxomics, proteomics, and systems biology.

Title:Single Cell Analysis in Biotechnology and Systems BiologyFormat:HardcoverDimensions:236 pages, 9.61 × 6.69 × 0.81 inPublished:May 20, 2016Publisher:MDPI AGLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3038421936

ISBN - 13:9783038421931

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Table of Contents

Technologies for Single-Cell IsolationSingle-Cell Isolation and Gene Analysis: Pitfalls and PossibilitiesDigital Microfluidics for Manipulation and Analysis of a Single CellNumerical Analysis of Hydrodynamic Flow in Microfluidic Biochip for Single-Cell Trapping ApplicationGet to Understand More from Single-Cells: Current Studies of Microfluidic-Based Techniques for Single-Cell AnalysisSingle Cell Electrical Characterization TechniquesMicrofluidic Impedance Flow Cytometry Enabling High-Throughput Single-Cell Electrical Property CharacterizationDetecting Antigen-Specific T Cell Responses: From Bulk Populations to Single CellsEvidence for P-Glycoprotein Involvement in Cell Volume Regulation Using Coulter Sizing in Flow CytometryA Review of Cell Adhesion Studies for Biomedical and Biological Applications