Single-Molecule Fluorescence Spectroscopy of the Folding of a Repeat Protein by Sharona CohenSingle-Molecule Fluorescence Spectroscopy of the Folding of a Repeat Protein by Sharona Cohen

Single-Molecule Fluorescence Spectroscopy of the Folding of a Repeat Protein

bySharona Cohen

Hardcover | November 2, 2015

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Inthis thesis single-molecule fluorescence resonance energy transfer(FRET)spectroscopy was used to study the folding of a protein that belongsto the large and important family of repeat proteins. Cohen showsthat the dynamics of the expanded conformations is likely to be veryfast, suggesting a spring-like motion of the whole chain. Thefindings shed new lighton the elasticity of structure in repeat proteins, which is relatedto their function in binding multiple and disparate partners. Thisconcise research summary provides useful insights for studentsbeginning a PhD in this or a related area, and researchers enteringthis field.


Sharona Cohen is a trained physicist, specialized in optical systems, microscopy and spectroscopy. She acquired her PhD at the interdisciplinary chemical physics department at Weizmann Institute of Science.
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Title:Single-Molecule Fluorescence Spectroscopy of the Folding of a Repeat ProteinFormat:HardcoverDimensions:59 pagesPublished:November 2, 2015Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3319095579

ISBN - 13:9783319095578

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Table of Contents

Abstract.- Introduction.- Methods.- Results.- Discussion.- Summary and Future Plans.