Statistical Methods in Environmental Epidemiology

Paperback | March 26, 2009

byDuncan C. Thomas

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Environmental epidemiology is the study of the environmental causes of disease in populations and how these risks vary in relation to intensity and duration of exposure and other factors like genetic susceptibility. As such, it is the basic science upon which governmental safety standards andcompensation policies for environmental and occupational exposure are based. Profusely illustrated with examples from the epidemiologic literature on ionizing radiation and air pollution, this text provides a systematic treatment of the statistical challenges that arise in environmental healthstudies and the use epidemiologic data in formulating public policy, at a level suitable for graduate students and epidemiologic researchers.After a general overview of study design and statistical methods for epidemiology generally, the book goes on to address the problems that are unique to environmental health studies, special-purpose designs like two-phase case-control studies and countermatching, statistical methods for modelingexposure-time-response relationships, longitudinal and time-series studies, spatial and ecologic methods, exposure measurement error, interactions, and mechanistic models. It also discusses studies aimed at evaluating the public health benefits of interventions to improve the environment, the use ofepidemiologic data to establish environmental safety standards and compensation policy, and concludes with emerging problems in reproductive epidemiology, natural and man-made disasters like global warming, and the global burden of environmentally caused disease. No other book provides such a broadperspective on the methodological challenges in this field at a level accessible to both epidemiologists and statisticians.

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Environmental epidemiology is the study of the environmental causes of disease in populations and how these risks vary in relation to intensity and duration of exposure and other factors like genetic susceptibility. As such, it is the basic science upon which governmental safety standards andcompensation policies for environmental and ...

Dr. Thomas is Professor of Preventive Medicine, Director of the Biostatistics Division, and Verna R. Richter Chair in Cancer Research at the University of Southern California Keck School of Medicine. He received his undergraduate degree from Haverford College, an M.S. in Mathematics from Stanford University, and a Ph.D. in Epidemiolog...

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Format:PaperbackDimensions:448 pages, 9.21 × 6.14 × 1.03 inPublished:March 26, 2009Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199232903

ISBN - 13:9780199232901

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Table of Contents

Preface1. A Tale of Two Exposures: Ionizing Radiation and Air Pollution2. Basic Epidemiologc Studies3. Basic Statistical Methods4. Multivariate Models5. Some Special Purpose Designs6. Modeling Exposure-Time-Response Relationships7. Longitudinal Models8. Time Series Models for Acute Effects9. Spatial Models10. Ecologic Interference11. Measurement Error and Exposure Models12. Multiple Risk Factors and Interactions13. Mechanistic Models14. Intervention Studies15. Risk Assessment16. Probability of Causation and Compensation17. Further ChallengesReferencesIndex