Stem Cells and Prostate Cancer by Scott D. CramerStem Cells and Prostate Cancer by Scott D. Cramer

Stem Cells and Prostate Cancer

byScott D. Cramer

Paperback | February 8, 2015

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' 'Recent evidence demonstrates that normal prostate tissue contains stem cells. There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells. Both the normal prostate stem cell and cancer stem cell populations have important implications for the generation, therapeutic targeting, and prevention of prostate cancer. The purpose of this book is to explore the role of stem cells in prostate cancer, which is becoming an increasingly hot trend in cancer research.
Title:Stem Cells and Prostate CancerFormat:PaperbackDimensions:182 pages, 23.5 × 15.5 × 0.01 inPublished:February 8, 2015Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1493900943

ISBN - 13:9781493900947


Table of Contents

Preface.- Stem Cells and Prostate Development.- Isolation and Characterization of Prostate Stem Cells.- Prostate tumor initiating cells.- TIC Markers and methods of characterization.- Genetic Control of Self Renewal of the TIC.- Therapeutic targeting of the prostate TIC.- The prostate stem cell niche.- Tumor stroma control of the prostate TIC.- Targeting the prostate stem cell for chemoprevention.- Stem cell models for functional validation of prostate cancer genes.- Index .