Stem Cells in Modeling Human Genetic Diseases by Mayana ZatzStem Cells in Modeling Human Genetic Diseases by Mayana Zatz

Stem Cells in Modeling Human Genetic Diseases

byMayana ZatzEditorOswaldo Keith Okamoto

Hardcover | August 21, 2015

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While most stem cell books focus on basic aspects and/or cell therapy, this book emphasizes the relevance of stem cells obtained from patients, the so-called "patients in a petri dish" as tools to investigate human genetic diseases for which there are no available effective treatment. Chapters embrace several examples of the use of iPS cell technology, a recent Nobel Prize-winning scientific breakthrough, to obtain patient-specific pluripotent cells from which many types of specialized cells involved in a particular disease can be generated, including psychiatric and neurodegenerative disorders, muscular dystrophies, laminopathies, among others. The text is a current and timely resource for postgraduate students, scientists and clinicians, interested in applications of this rapidly developing field of research in disease modeling, drug development, and emerging issues that it brings to regenerative medicine.
Dr. Mayana Zatz is a professor of Human and Medical Genetics and is currently the director of the Human Genome Research Center and Institute of stem-cells in genetic disorders, at the University of São Paulo. She completed a Ph.D. in Human and Medical Genetics there and was a post-doc in medical genetics at the University of California...
Title:Stem Cells in Modeling Human Genetic DiseasesFormat:HardcoverDimensions:147 pages, 23.5 × 15.5 × 0.03 inPublished:August 21, 2015Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3319183133

ISBN - 13:9783319183138

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Table of Contents

Modeling Fragile X Syndrome in Human Pluripotent Cells.- Induced Pluripotent Stem Cells in Familial Dilated Cardiomyopathy.- Induced Pluripotent Stem Cells and Amyotrophic Lateral Sclerosis.- IPS Cells and Spinocerebellar Ataxia.- Induced Pluripotent Stem Cells and Vascular Disease.- iPS Cells and Cardiomyopathies.- Cancer Stem Cells and Chemoresistance.- Stem Cells in Autism Spectrum Disorders.