Steroid Hormone Action: Frontiers in Molecular Biology

Paperback | July 1, 1994

EditorMalcolm G. Parker

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Steroid Hormone Action is a comprehensive overview of the molecular mechanisms by which these hormones regulate the expression of specific target genes. The book covers the structure of steroid receptors, transcriptional activation and repression, and also contains chapters on steroid bindingproteins and steroidogenesis. Steroid receptors represent one of the best characterized transcription factors so that the book will be of general interest to Molecular Biologists studying eucaryotic gene regulation. Chapters on the mechanisms of action of steoid antagonists and defective receptorsin target cells will be of particular interest to Endocrinologists and Clinicians. In such a rapidly progressing field it is difficult to keep up with all the literature but this book, written by international experts, focuses on the most important advances that have been made recently.

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From the Publisher

Steroid Hormone Action is a comprehensive overview of the molecular mechanisms by which these hormones regulate the expression of specific target genes. The book covers the structure of steroid receptors, transcriptional activation and repression, and also contains chapters on steroid bindingproteins and steroidogenesis. Steroid rece...

Malcolm G. Parker, Staff Scientist, Imperial Cancer Research Fund, London.

other books by Malcolm G. Parker

Format:PaperbackDimensions:226 pages, 9.69 × 9.69 × 0.07 inPublished:July 1, 1994Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0199633924

ISBN - 13:9780199633920

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Table of Contents

1. Extracellular steroid-binding proteins2. Importance of steroidogenesis in specific hormone action3. Overview of the steroid receptor superfamily of gene regulatory proteins4. Role of heat-shock proteins in steroid receptor function5. Nuclear hromone receptors as transcriptional activators6. Repression of transcription by nuclear receptors7. Structure and function of the steroid receptor zinc finger region8. Mechanism of action of hormone antagonists9. Mutations in steroid hormone receptors causing clinical diseaseIndex

Editorial Reviews

'recommended to molecular biologists, endocrinologists, pharmacologists and clinicians active in this field'Aslib Book Guide