Stimulation And Inhibition Of Neurons by Paul M. PilowskyStimulation And Inhibition Of Neurons by Paul M. Pilowsky

Stimulation And Inhibition Of Neurons

byPaul M. PilowskyEditorMelissa M.J. Farnham, Angelina Y. Fong

Paperback | August 23, 2016

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Activation, inhibition, or destruction of the nervous system or its component parts as a vital tool for the investigation of function has undergone remarkable development; indeed, new approaches have been developed that allow for these actions to be used as therapeutic tools. InStimulation and Inhibition of Neurons, experts in the field provide an overview of modern methods for generating lesions as well as for stimulating and inhibiting neural pathways. Many new techniques such as optogenetics and the use of the in situ perfused preparation are examined, while, in other sections, the use and validity of more well-known approaches are reassessed. Written for theNeuromethodsseries, chapters examine their respective topics thoroughly and include the kind of detail and implementation advice that ensures successful results in the laboratory.

Authoritative and cutting-edge,Stimulation and Inhibition of Neuronsserves as an ideal guide for researchers seeking to gain further knowledge of the complex functions of the brain.

Title:Stimulation And Inhibition Of NeuronsFormat:PaperbackDimensions:319 pagesPublished:August 23, 2016Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:149396268X

ISBN - 13:9781493962686


Table of Contents

Part I: Novel Experimental Techniques

1. Optogenetic Stimulation of Neurons in the Brainstem of Freely Behaving Rats and Mice

Stephen Abbott

2. Stimulating Peripheral Afferents to Evoke Cardiorespiratory Reflex responses in the In Situ Arterially-Perfused Preparation

Angelina Y. Fong

3. Excitatory Responses to Microinjection of Glutamate Depend on Dose not Volume: A Meta-Analysis of Studies in Rat RVLM

Andrea H. Gaede and Paul M. Pilowsky

4. Acute Activation and Inhibition of the Sympathetic Baroreceptor Reflex

Melissa M.J. Farnham

Part II: Intracellular Signalling

5. Pharmacological Dissection of G Protein-Mediated Second Messenger Cascades in Neurons

Mark C. Bellingham

6. In Vivo Manipulation of Intracellular Signalling Pathways

V.J. Tallapragada

Part III: The Single Neurons

7. Identification of Spinally Projecting Neurons in the Rostral Ventrolateral Medulla In Vivo

Simon McMullan

8. Microionotophoretic Study of Individual Neurons During Intracellular Recording

Qi-Jian Sun and Paul M. Pilowsky

9. Neurobiotin Electroporation for Combined Structural and Functional Analysis of Neurons in Developing Mouse Brain Slices

Refik Kanjhan and Mark C. Bellingham

10. Juxtacellular Neuronal Labelling, Physiological Characterization, and Phenotypic Identification of Single Neurons In Vivo

Anthony J.M. Verberne and Ida J. Llewellyn-Smith

Part IV: Methods for Analysis

11. Analysis of Sympathetic Nerve Activity Analysis of Sympathetic Nerve Activity

Rohit Ramchandra

12. Insight into Autonomic Nervous System Control of Heart Rate in the Rat Using Analysis of Heart Rate Variability and Baroreflex Sensitivity

Cara M. Hildreth, Ann K. Goodchild, and Jacqueline K. Phillips

13. Neurophysiological Recording of the Compound Muscle Action Potential for Motor Unit Number Estimation in Mice

Shyuan T. Ngo and Mark C. Bellingham

Part V: Clinical Focus and Application

14. Animal Models of Neuropathic Pain Due to Nerve Injury

Paul J. Austin and Gila Moalem-Taylor

15. Detection of Sensitized Nerve Responses: Dorsal Root Reflexes, Live Cell Calcium, and ROS Imaging

Karin N. Westlund and Liping Zhang

16. Visual Evoked Potential Recording in Rodents

Yuyi You, Alexander Klistorner, and Stuart L. Graham

17. The Visual Evoked Potential in Humans

Stuart L. Graham and Alexander Klistorner

18. Improving Motor Activation Patterns after Stroke with Wii-Based Movement Therapy

Angelica G. Thompson-Butel, Sarah E. Scheuer, and Penelope A. McNulty

Editorial Reviews

From the book reviews:

"This is a neurophysiology laboratory manual with step by step instructions on how to record from preparations in vivo and in situ using the rat. . This is a timely and excellent contribution to neurophysiology methods of great interest for students, postdocs, experienced investigators, physiologists, and neuropharmacologists." (Joseph J. Grenier,, March, 2015)