Strategies And Tactics In Organic Synthesis

Hardcover | August 12, 2015

byMichael HarmataEditorMichael Harmata

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Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project tell of the excitement of conception, the frustration of failure, and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done. Readers will be educated, challenged, and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs, and building molecules with atom and step economies that provide functional solutions to create a better world. Presents state-of-the-art developments in organic synthesis Provides insight and offers new perspective to problem-solving Written by leading experts in the field Uses firsthand narrative accounts to illustrate vividly the challenges and joys involved in advancing the science of organic synthesis

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Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and t...

Professor Michael Harmata graduated from the University of Illinois-Chicago with honors and highest distinction in chemistry.In 1980, he began graduate studies in chemistry at the University of Illinois-Champaign/Urbana where he was awarded a University Teaching Fellowship. He worked with Professor Scott E. Denmark on the invention of ...

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Format:HardcoverDimensions:442 pages, 9.41 × 7.24 × 0.98 inPublished:August 12, 2015Publisher:Elsevier Science & TechLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0081000235

ISBN - 13:9780081000236

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Table of Contents

Preface,Michael Harmata1. Acortatarin A: Spiroketalization Methods and Synthesis,Barry B. Butler, Jr. and Aaron Aponick2. Devising New Syntheses of the Alkaloid Galanthamine, a Potent and Clinically Deployed Inhibitor of Acetylcholine Esterase,Martin Banwell, Joshua Buckler, Colin J. Jackson, Ping Lan, Xinghua Ma, Elia ka Matoua ováand Jeremy Nugent3. Discodermolide: Total Synthesis of Natural Product and Analogs,Jean-François Betzer4. A Walk across Total Synthesis of Mycolactone Analogs - Mechanistic Implications in Mycobacterium ulcerans Infection,Nicolas Blanchard5. Total Synthesis of the Fungal Metabolite Virgatolide B,Paul A. Hume, Daniel. P. Furkert and Margaret A. Brimble6. The Role of Serendipity and Design in the Development of Oxidative Coupling Reactions,Brenton DeBoef7. Overcoming Electronics with Strategy: Development of an Efficient Synthesis of a Novel Antiretroviral, BMS-663068,Ke Chen, Christina Risatti andMartin Eastgate8. Synthesis of Alkaloids Containing a Quinolizidine Core by Means of Strategies Based on a Hydroformylation Reaction,Nicolas Girard9. Total Synthesis of Sorbicillactone A: An Inspiration for Methodology and Catalyst Development,Kelly A. Volp andAndrew Harned10. Total Synthesis of (-)-7-Deoxyloganin exploitingN-Heterocyclic Carbene Catalysis with ± ,² -Unsaturated Enol Esters,Lisa Candish and David W. Lupton11. The Realization of an Oxidative Dearomatization-Intramolecular Diels-Alder Route to Vinigrol,Cristian Draghici and Jon T. Njardarson12. Total Synthesis of Communesin F and Perophoramidine,Dan Zhang, Hao Songand Yong Qin