Structural Biology Using Electrons and X-rays: An Introduction for Biologists by Michael F Moody

Structural Biology Using Electrons and X-rays: An Introduction for Biologists

byMichael F MoodyEditorMichael F Moody

Paperback | January 19, 2011

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Structural Biology Using Electrons and X-Rays discusses the diffraction and image-based methods used for the determination of complex biological macromolecules. The book focuses on the Fourier transform theory, which is a mathematical function that is computed to transform signals between time and frequency domain. Composed of five parts, the book examines the development of nuclear magnetic resonance NMR , which allows the calculation of the images of a certain protein. Parts 1 to 4 provide the basic information and the applications of Fourier transforms, as well as the different methods used for image processing using X-ray crystallography and the analysis of electron micrographs. Part 5 focuses entirely on the mathematical aspect of Fourier transforms. In addition, the book examines detailed structural analyses of a specimen's symmetry i.e., crystals, helices, polyhedral viruses and asymmetrical particles . This book is intended for the biologist or biochemist who is interested in different methods and techniques for calculating the images of proteins using nuclear magnetic resonance NMR . It is also suitable for readers without a background in physical chemistry or mathematics. *Emphasis on common principles underlying all diffraction-based methods *Thorough grounding in theory requires understanding of only simple algebra *Visual representations and explanations of challenging content *Mathematical detail offered in short-course form to parallel the text

Details & Specs

Title:Structural Biology Using Electrons and X-rays: An Introduction for BiologistsFormat:PaperbackDimensions:450 pages, 9.25 × 7.5 × 0.68 inPublished:January 19, 2011Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123705819

ISBN - 13:9780123705815

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Extra Content

Table of Contents

Part I: Fourier Transforms

1. Overview

2. Correlations & Convolutions

3. Fourier Fundamentals

4. Digital Fourier Transforms

5. Filters

6. Two-Dimensional FTs

Part II: Optics

7. Microscopy with Rays

8. Waves

9. Wave Imaging

Part III: Further Mathematical Methods/General Aspects

10. Symmetry

11. Statistics & Matrices

12. The Third Dimension

Part IV: Image Analysis/Structure Determination

13. Special Symmetries

14. Crystalline Sheets

15. Helices

16. Icosahedral Particles

17. Unsymmetrical ("Single") Particles

18. Distortion Correction

19. FT Mathematics

20. Elementary Matrices