Synaptic Transmission: Cellular and Molecular Basis

Paperback | March 1, 1994

byHerbert Zimmermann

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A comprehensive, up-to-date review of synaptic transmission, covering all major aspects of the subject, from the biosynthesis of neurotransmitters through release mechanisms to receptors and signaling. Zimmermann also demonstrates the integration of recent discoveries about the nervous systemof higher animals into a larger picture that notes functional and structural similarities between neurons and non-neuronal cells, primitive neurons and even plant systems. This area, which is advancing rapidly, is a topic taught at some length in all neurobiology courses, and could also be thesubject of an advanced seminar course. An outstanding overview, the book cites virtually all of the important papers in the recent literature, and the accessible text is supported by numerous two-color illustrations and section summaries. This book would serve as a supplementary text or primer inthis area for graduate students and for investigators in related fields. Because it gives more current coverage than is readily available in neuroscience textbooks, the work may also be useful as a monograph to some neurobiologists.

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A comprehensive, up-to-date review of synaptic transmission, covering all major aspects of the subject, from the biosynthesis of neurotransmitters through release mechanisms to receptors and signaling. Zimmermann also demonstrates the integration of recent discoveries about the nervous systemof higher animals into a larger picture that...

Herbert Zimmermann is a Professor at Johann Wolfgang Goethe-Universitat in Frankfurt, Germany.
Format:PaperbackDimensions:160 pages, 9.45 × 6.61 × 0.28 inPublished:March 1, 1994Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195210735

ISBN - 13:9780195210736

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Table of Contents

1. Introduction2. The structure of the secretory compartment3. Synaptic transmitters4. Cotransmission5. The secretory organelles6. Biogenesis and life cycle of neuronal secretory organelles7. Electrophysiological analysis of release8. Exocytosis and endocytosis9. The superfamily of ligand gated ion channels10. The superfamily of G-protein-coupled transmitter and hormone receptors11. Second messenger cascades12. Inactivation of synaptic messengers13. Mechanisms of synaptic modulation14. Electrical synapses15. Glial cells are neuronal targets - and vice versa?