Systemic Treatment of Non-Small Cell Lung Cancer

Paperback | June 7, 2012

EditorGiuseppe Giaccone

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Lung cancer is the leading cause of cancer mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for about 85% of all cases of lung cancer. Most patients present with advanced disease and five-year survival is low at about 15%. Surgery is the main treatment for early stagedisease. If patients are deemed inoperable, systemic chemotherapy is considered. For patients with locally advanced disease, multimodality therapy is administered where chemotherapy is given in combination with definitive radiation therapy or surgery in selected cases. Cytotoxic chemotherapyregimens mainly consist of a platinum doublet. Biologic agents are increasingly being incorporated into treatment regimens. This pocketbook summarises the latest evidence-based and practical information on the use of systemic therapies in the management of non-small cell lung cancer (NSCLC), for early stage, locally advanced, and metastatic disease. Including contributions from leading thoracic oncologists from NorthAmerica and Europe, the book covers the range of therapies currently available to clinicians including cytotoxic chemotherapy, biologic therapies, and other novel agents. This book will serve as an invaluable reference for all health care professionals involved in the management of patients withNSCLC.

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Lung cancer is the leading cause of cancer mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for about 85% of all cases of lung cancer. Most patients present with advanced disease and five-year survival is low at about 15%. Surgery is the main treatment for early stagedisease. If patients are deemed inoperable, syste...

Giuseppe Giaccone, M.D., Ph.D. is an internationally recognized expert in the field of lung cancer and developmental therapeutics. Dr. Giaccone received his M.D. cum laude from the University of Torino Medical School in 1980, followed by training in clinical oncology and internal medicine, which he completed at the University of Torino...

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Format:PaperbackDimensions:128 pages, 7.09 × 3.94 × 0.68 inPublished:June 7, 2012Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199580480

ISBN - 13:9780199580484

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Table of Contents

1. Adi F. Gazdar, Jill E. Larsen, and John D. Minna: Molecular biology of lung cancer for the clinician2. Sofie De Craene, Kurt G Tournoy, and Jan P. van Meerbeeck: Staging of lung cancer3. Benjamin Besse and Jean Charles Soria: Systemic therapy of early stage NSCLC4. Margaret Edwards and Hak Choy: Combined Modality Therapy for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)5. Taylor M. Ortiz and Pasi A. Janne: Systemic therapy of advanced NSCLC, efficacy, and toxicity6. Paul Wheatley-Price and Frances A. Shepherd: Systemic therapy for recurrent NSCLC, efficacy, and toxicity7. Paul Baas and Wilma Uyterlinde: Palliative care in NSCLC8. Arun Rajan and Giuseppe Giaccone: Development of new therapeutic agents for treatment of NSCLC