Systems Biology and Synthetic Biology by Pengcheng FuSystems Biology and Synthetic Biology by Pengcheng Fu

Systems Biology and Synthetic Biology

EditorPengcheng Fu, Sven Panke

Hardcover | April 20, 2009

Pricing and Purchase Info

$207.30 online 
$229.00 list price save 9%
Earn 1,037 plum® points

Prices and offers may vary in store


Ships within 1-3 weeks

Ships free on orders over $25

Not available in stores


The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.
Pengcheng Fu, Phd, is a professor in the Faculty of Chemical Science and Engineering, China University of Petroleum, Beijing. His research interests include: biofuels and bioenergy, metabolic engineering, functional genomics, genome-scale modeling, bioprocess control, metabolomics/metabolite profiling, systems biology, and synthetic bi...
Title:Systems Biology and Synthetic BiologyFormat:HardcoverDimensions:672 pages, 9.5 × 6.4 × 1.35 inPublished:April 20, 2009Publisher:WileyLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0471767786

ISBN - 13:9780471767787

Look for similar items by category:


Read from the Book

%PDF-1.3 % 1 0 obj > endobj 2 0 obj > stream H|Wn#}#?fy6H6%5b*,?`1&S>n??]8/ d]hfyv9n?of|W6^fr+kq\?IbZ?wt\S[u&L]?ih$,&H+-[g:^s?l[mC q:>;N[=yPxjR+jQ 9!_=,G3O-2Z?82]n|?uk?kNj>O:xsU%x #b _Vi]$LuXSwUB2:?0?>MSZf&4Qlm5 Vec@?g!h??? )/iA?sc44RQ;Jy5IHT2CbBB^A%~VP6??/#J:F^s1%yo:2~nrRlEA>9+)2qk 4cHUjSiIkU%eZOVtLC 0hLaR2Y?Lj?f(ZZ(d?rE?XvY%G_@]Ih#zUuGJi; .oD?PRfO{Life4[RR] QJ?A(( iD")MP?LzQ~`ug^4_?dL\4i? ((X?$\Fm+0*l3KV30 ?h;C O :V;|? t{OYEDg| !/x rT7B)@z-QCj!nh tkB]\Ny3xV]Y:.XHIKQAD1x*Lf^;\(=v.7_,JH%]~8eSK*KwmDQt?R,?e&S RvE?">{?CIt?(i83u0.JIc$WP$Kg! Hx%i\%G:Q/?z[(] :i2 `?MbT6CWMyP$h1nNH:w1&wn!@im?8$s?p w#^ QCD29Iq?k;$~Y0{/XlY xQxN1e62JrEL\ e#mY23 7Y[V_$uwfit~MVICcf:;\Xf?`j"9y4S"_$U+$?jn3ERh"P^UEV"7Le_eK*02?9?. QÁ9A274?fq*99D"F@:86ActUE/+V&PnI1(:&.e}, vO_nDO|{89ri/Y9 endstream endobj 3 0 obj > stream HTSkPTeUw%\@6@\ *FEij:`7DA,%/1NM5(d?{0Y4y{yeFEy9!!)~nz@|A- > stream HW?}c+il^` }8TKl"^f ?4W.KjwV?_?cO?> ]?tU9YoG{fJ 4?=f? no C sWIzC*zywzFoMOw~~}??d~cM/\tbFG}Z5?ep,/Gk?G_kzq^\f/G%u179& 6&[U5iaA''6x.:X?4 );qmu*?``k U:M9, :`??o7u^K*?w_ ?sr&bqQFkf~(dU:N,-}{~VZtTU +j2s}=0e !A;s?b''Z},kTu?daF5| WeKtL ;*1;DVm9uV;V]|''Tgj!$w/@Ff^us)av''''t F?n{e$x2LM  SM0?\o8_JL~mm2! > Zq?{ 10[&%?b |{ Y:`i9w $Se{:[^*eps"IR&a+h?@*oZQE8u8vsoha.6 $ ?-P;z>LB[>NY c()?=r?t>) R(= ere](/&>%*M ??*i2\ta?ZuK9Xq/R*?E ?92?7/tMOq,LRZ !(q[,/4ss|RR ]:2 i)?J )s g|kn%BQT,4k''SE2?:Kd O !RK4{tnqBd~ZJ??{ ,h'' D,\zlZl?RB?$?2JhyR%kq\5US*H@!~2Up? D+SVi? IEYxe?5@?Q?8uNF):mBMEWS5,S-9?l**1~+NJ, |u 8k(P^\ si |g?>~0SYOn )K?m?a`\L CsG.XmzDra/S\0*iPY 99i,0&?w5Gw)Sd!?# @LCL?(/Ik2lx,F ;"KBBAr?''>uzI%Q)V@ r;F{?&IwZW??fI8d$ Ra4\A w`_:R4S? kyFKd2u:b#r6ko>UL9"\%R9DNwKCf: ??o#qP*???!s5)-?-.5d\ W&bmQw?,[)`,0HSn \.b/t?rjb $q6*Rb sY38[jub~k5Hjp?Ob}r??''U !m*N]%KL?x?@hh!(s?Buoa-+L6On5g?HZ8bu# k(S^q&|y e2a M''8SIz ,P.6OtP`p(''QU(+b&r>T m1kj?U"wZv6>_% 4/?-lpE1E h9?LS;q.?=ym 8kJ:&4wF''}Tvv&o |9!n/o''?6YJpf.li8CKpNx6>r.;6Nnj\2PreR`rYH=&RoHlR%i?z? V@r)3 V_b ?fj,S!6#f ?4YC|?4oa9?ME1M;zk>>{ay ?nbK|hS* S{+tXY#?5$x-!UihVU4J??J`. ?-\k- +T?5?=?y/v7 endstream endobj 5 0 obj > endobj 6 0 obj > stream BBEDDC+AdvP4C4E59 l|C19AdvP4C4E59! yy| -y endstream endobj 7 0 obj > endobj 8 0 obj > endobj 9 0 obj > /ExtGState > >> endobj 10 0 obj > endobj 11 0 obj > endobj 12 0 obj > endobj 13 0 obj > stream HW]o|(~1bb#AaD)!);.?8UXr?=|)*8]?(.mV4?v?X??B;ue;Mw\Qn _?Y?Qa}n/????*J|55?qVUjPfue:/Px? v__{uq#^2B63nuo?Sn6;amk7Ql?V8,9&k ''6%6b(xlDLK8K0ye 77x+4]t_f8$5P1>lnpGnxf?nU3PK4e?S\]~b&,KO0RxR r"a:n W_n)Muhu f"rWI`?''Ui#7)dF2E/Y|@WLþ ^.|(%?{A2f Nvg`&L %d =?Jc? R$ YHj-Y8 f[*ZpaA2B-i ?o+?1#Wf}UR4Min? aS(?b ut1vI3??)9r16]G6 O.g+c 3CgNK:?B+^RG!Hzk''|} q`GEq]I (?RO*?1oTQt%_pvggT:Qtn=qEf?0Axy:Qwtp%Qdt +miK >+g *;6%S?L]+2Ve*"?aEj !Pmzn}[s[(3b?|RnU>N+8(.?e)1 @0QhzB\A}?]_6b?|c?J` lr~hBfqOm\y)W? J6.{ ,v?6!; M _[E5S?"~o^ISat Lqk|R\ {w_XOµJ}7!hQJG11_?wm endstream endobj 14 0 obj > stream H Ax0UQt%iU7Q RWVSp qP?LJpb\I?@ diAl¤.Si?{UqZ5R?YYI ^eoES?S#U1FS/T8MTsS\8E(5qJYN?pk87@?SUgk?_AijSkFB\"b&*?e`(b?}:gHoFA3]'' x|?k%''oE$`#n7cW9^X^SIu7*t--w0pNHb[ b^Zi*''D$`HCqzlmco"Oc@`+/{lWSOS??,tcL&` VxU`J&#y?dfzN clj I0r\> @t&g^?r.ayu, _8? endstream endobj 15 0 obj > endobj 16 0 obj > endobj 17 0 obj > endobj 18 0 obj > endobj 19 0 obj > stream HtiTWojPATDeEl#\?(k#f?+J,nFee9?9g2}{-B$I\]]7.t Mi:bf29FUFwA7 ,bTXM83AH GHyAS!?''"}C(?>??z-?3_gN?ORT?mL''cbB$n=Ho^X>C1Skf ?o?%;X+2@uc?`lt?xEq^W+kw|?œ^aY4%;1u9>?sz(*RJ8etaJepE?#1g~wB8`w]=3s$7A,kt6_(;a RB[ RPPtyg^!3gAZbiLu3"#cbT 5pNc?B{w&%IcsL4F "*6."EQV1AKCz,) l?r ;K)=!]:-Tk@\[V sMKvZ0?E?:yuN_R^PE3O^($g!Ld2evV;*pY**?nhxqA.?~ FO7 tRp!9Rarj"4_/sW$az9FW79d;mJ?a5MYmDC?Rt P@''k!%rKM^ 1T[d ?T?r.??l-MKJR#\\TÜ+N+R h Me??l uh3H_bOkOT!,YvV+ :j&`{Op Q?q? HmPizTQU ?-?_9mLlWkTT,[5?vkAc"*;(DE,*x`x3 wxcf`xF^gh5$6vu&&{?V]]?l *n6KF6CpB?Mj`,RBi*nK$ahcaULI?2#sF}O$H%iT1I{o? Xc>%f%A5n G"WtyK~*%.YQ*IsTq?h BrF ; 3A:?bZha*-v]$,S%18%hr -H:eLs*r)>/uA,3e@O*hgA(Jqo7|RIr@DI?|ÑBE?iyLUgCE*?d n~b?W$p{\.=V?yJc5"F[A#xXm=7p0 V3.(l?3 8 gQ/%AOMW??T95\[ `\?DJp,.?] ?UqF:mKa=A^AyR3Y]y5A qA\ptbm@vU3:}pM_yW~-xqN?El)vs!05?L>|S5203N=T -E?BmgHO(''M6-$J;ll?N$}rcActaLLC!>Pk}f|¯?1:;+Fa@Gf6''Kmm" [Q@tZn{N8X8?:??V=32#)?GDN?-9=cn`m I ?{`yA@!& atr&"#RF K?%1:+4?l]{pz?2$$zo.[m \?P''X6[by]Y;wx3EGWGw(a6+u~1F# Gv&$8tFOw H"p jx1[W,}Lpm~1N^kqM_p?xWF*K''+S|zD(sKF\i7>?&''P/CV.heH&s^Sg]o [5dbrroC=+rStKW,m`{HZ\-)e;x?8?gj?-Z!lGh? bW 0)uuw"?hQ,A>9kiG?1I]Ln0|P.S&j Op!6B/?cNH''7?454b-/jK/TS9cZ5J ?OR^e$@PbNB`$$&3(|w0L")q^tOLTJeg$2(k4}r_B $?k''80K''0(09X ?NO-HOo$xNnG`u|nR~xO`Gw|m&A(kO''NMf¦fZfZ^s@qOA 2W!=*rS? /S$R5lhz75hd3w8p÷=C s fhk^8\%()v4zh{?1QC Z@F~ ,v#GAzvlZóTLSpGB\vw[Z T:w7t= gP^?,}*Tn`NS&ew`?,5{ FD i \?.?B =(jq:?m4 DAhtQ.{p+iD:hpF?)TÒ:KIh%?I#n91!RB1,hvZT1?uKvt^C6 ?$C:daS{yoyDX,4J *N_\[NBs[ASY:57UBF_?l`;/S|? > stream HW]6|GjWA99]? eP*?%k+WyA fzz? TX{x?n{q }ltW/4e? }?~V `U)f?1~4,\EX[9-9Hm[~a/UK('XK0E5g.T)e3{?3iT}(YV1 -4 ;=7"? ''~?B84g;E?h/xdN''h>"YY@7G>?PN ;h, zly?mN$dC|F?naH;B.? )z&B^hR|4jcya?bU TgHïYfbkvObsvD?qrC8 aZ4oJ P. M;%lww/IE\Xv/|662b+ fI+Q7&E!m>]N1lc?b,m(cz^zb?$)Y KNW"6E*[i~''#OedCB 1?Db`n#ra6h BBY*p {MYE"D|j !*n!V*XKp98I; _>C+ dX !#?*]y $/Ae(m@I^UQWix:HVL~;rOlc"c^e)j{ue{8}J_cT*_m_nwOny4j7q+? ?L+Qt/J_;9*6|xA0~`qr? l0?/]-mQtRj!GTvE^ 7E>{gH?w9= P?/K;TKH%sjnùya2NIpejD?kO(a8|\`iRV^1qQ/X ehb?bC(98om"l*/WS+/?u`\T.k*U/|RY%fKaQ.~FTv?dL?8''-/Q y=W#sf6S55 Ly?I1Xju0{?=p #,^G?IUC1>f$QXE"u|yj;)mo&e.e -TMN>9vKg?)?lmi}PZ=G?o f.bp:r,. ,ZWp @k +j6!oeE,U??^?q?*q?D8 DW$$\q}> $"bvJ4jG|cn?QD?CM.6!k`981YUgz*`&?~^?~ ,%p\Y?3?? ?-{2 $?4giDh;1Sw 97!|/8WjO,U`dY*?kkh(c1~Jsà #@ %8Ah]?; VuÃ[Ea nF?X?")XX°.[>3l MEK''"zBW*TZH#0?v g$fSg''~?-2?5gC > endobj 22 0 obj > endobj 23 0 obj > stream H|Wr}Wq!C?IQt,Rq@,vw,,`ES9=^''*jv?On,.Ur({4L4/0Imz^D?? $R aMWyhUYu??VZRs-[7'';72k?kUpjjW^r??t[vJ^*)q?xMeCFUXN,9?k?g?IMe>Ao8Lp 7l/5V  |D8XT\aM|U _)^ }6 66jmT?L,mLJ#"?=>P ? 5oSO~{"eH8"n|/)r[ULv? 0c5>0G]!s ukW:T5d KCp/H DI-CzB?uDB2Ej?0X~|Jd?{ )["gs`{bi@5okZl''`@/_},@SSN Fuy0fv^ZX>HD{Q-?Sc jmvm ?%bC?Z,"0*a[ftKQ1p10T +OEe_"S3Hqix''HO''p~G?7?934Ia!yC%S e4 PòL-,zy_68f{?B?k~RxX9j|(c s8f=B$b?7r &3?1}:! 579?8/@>^ > stream HTTyPwn0=?W4Y ?D/@/jkaKa (R {t?`#?z=]>l.klF)y7a?4LAa?>;?fo|o],`P?Hq4\=)lM7:+ tC5q:IR`?sTnNz~00/I6OnVUF VhEm];;$ T3z^QHS?lRa?aGJA7Sa0x? ? v{XQ&O}H??/_R"Mau;VvwfXR*{Y7&cAO\^?Fa|4!dUVda.bc(]b_{yudh:$e ?\S??P}tl0TA1cE7?tTQ5m&4Yx @[91Eo010deM}YCv:S7 %:=J(Xe *?)?7bEvT_R&` ~nv?M?Up&%LI/-/,{ zKzTo ?qL:C?2{qQkD5?~N@E2X{mKm?-10PZDXc_?pbK2Wk,T9xi57Wio{WC>I+9#[yP=ld$>^^\&?R^U:e&v ??rl}d#|Y7L6}[''VAQ|TH''[nik+Lio t$a!.//r mkLwD?T`~#:,8) n?\G{QA"HXqKBy p.?1VA$He)Uo~?''$#| U.KSv7z?#cHBàN?QB/?j~tHaoQh0:gxDaqV#rUXY2V$ {?.kP+ 5#`l5G?w)6`_\~xtW*[BTVJF482L_?~D pbQ;~QD?U?u,c|(vN#Hj6] sH?t.MC59N }|E s;c\]G 9r|X0lws[HRn i[JA)X~%gsBRNFgD=  (hhUj''3.aq8+.1D +k ?3i[w  |kkx3>gy4ci`  l?pCi ?@s#=#A??eb)!ER(M}|M3=6BV;Jtq#rES__Bl.`RRRZ*+{?p^GEcV D.yh|n?|^!(t{\?PEe ?''N5[{OzCD zCcR TUPDsaBpIll4@E:>S9??9XMH?XHJ51 zx-{wAQ*V7nqY8H?D a v 5s>ey_9vy/YiSia{.!e??]L,?E]?k:''?Po@-~FL?9CQzG]xW:>wjlCN?T nBz;yH?` dJ>~!)f~x2XY]_´x` C`$ r=`!T. zQ_''-"R?4 )4]#*kt$ ?3,;Z^arAC,VAU+N-IO?t;N^A, Uee%*N";B# ,r@V? MTED6U6T;=xW\N9Wy|ukIsp|}l1qizyyuvy{sy? V~$E`0UCeqaZrnci~{y~mwzzva e wfqv}]bV > endobj 26 0 obj > endobj 27 0 obj > endobj 28 0 obj > endobj 29 0 obj > endobj 30 0 obj > stream Arbortext Advanced Print Publisher 9.0.114/W Unicode E1CH01 1..8 endstream endobj 31 0 obj > endobj 32 0 obj > stream H endstream endobj 33 0 obj > endobj 34 0 obj > endobj 35 0 obj > endobj 36 0 obj > endobj 37 0 obj > endobj 38 0 obj > endobj 39 0 obj > endobj 40 0 obj > endobj 41 0 obj > stream Hbd`ad`ddrrru vL) 0q6q57+i/ vWIp#E LL|?^%}5yWt^} yr^^[]^>{w by3 4B endstream endobj 42 0 obj > endobj 43 0 obj > endobj 44 0 obj > endobj 45 0 obj > /ExtGState > >> endobj 46 0 obj > stream Hbd`ad`ddprruvL) 04w{X/_^!ldhWfs?fv?UL[kd)]XaD}c\Z^oo 9=\C%*Dsgk.wzuw0[( z@,YwY ?e!Fd endstream endobj 47 0 obj > /ExtGState > >> endobj 48 0 obj > endobj 49 0 obj > endobj 50 0 obj > endobj 51 0 obj > /ExtGState > >> endobj 52 0 obj > endobj 53 0 obj > endobj 54 0 obj > stream xYrF}Wi a`DRjk+IAE2{N"Tp}9}z[Wb{e0O"0Q"M* Zf^a + L0dV07[-o?S Þkl[ZD:w}q;?JEZ*aaq''|_~>?''D''rcFIsw?%?jJn8Ra|N;2rLP.iLi(f O+4!0{i0p8X* {CRZs4I?n4êa*j6Ss(J_y}áqsc?&2JY(f-T/iS Z0@fVP} 3)v?0^pU?1:gMX}=O*XuUg) ZlSHoiku?h? ~9:?6gtCW0d>b;Kh \Ç0V{,8.UT!^(?6??!?T8,w;OFu)''sJW%"Q"#hSjj''0v=^s\Z m%?k ` 1Y jAr??r}Ub> pfqtBQ~eP:gz?\?P_E2?YUzD,!t^N6=}mP q?%DRP5p+Bb;x/xx#U:+JC0(rlR4jUfub t-%?U?KAs ZQ5 JFm/(-4_ )(CjJKLCki9j|?OqfV ?K WKr{S #\6[*b$X,?ù?teix4 Ar&KyWL/K;Jw%@%ye4CK-%#!>7Ep¤3Hutg"E 4e4K?\J?Bso?bPIADat+V +:MGKp fe (vCCF?bGc[h1Zm?QCk^X $&VJG^K??3S}z}(9\bCr_Zka +[5*@&Y=g# S9kshDo|S|]rAmj(??\3 ]K#ab=?ANqw@|ftu?/r?6?O''Z .]L&%rx3tNj_t!(,r?`,8v?K0z8BZ:H2 dYgEJZ7o#Ml"E?v"PXs"PG({m+}TwP5wP;\@@{?E"ON zz?#OEnsTNft| BfB$=3?l;$@7M Vh#G&!Dn/ %ViWu 7sj9E&ffg":c `a.;I("?5/{i{%F^A/k?6Rl2;WCv.M?nKOy| ?M bO"1*Hp?;l~|RCbX,?W|?1c P7}WE__>/ 8!?(? J>''X0t~ endstream endobj 55 0 obj > stream x] wYg(nA W4n!/LX?Q/# L[{&DVy?uKU[N?o ([]S}{_NT^ 4?oUi,0 ^l &?uXyw #w $/Kz?J\?''aqWya le)[ bzN[PBO(OQU;Ui+{[w2(u${R#C@^O3zA1&$ Y''9Lw$@? +~3[? 3a |k@_68''d"z?`p.@`8''Kb[1~l4?8bz>?7=[=5,+FBL ,# ^7s.?1or/&{;colNldoe4wWy&{BL?=kbh?{ Y?6nPgY"Ql?:L ;KCLpWl=-3A S b^ HZ=^r#`q|ý)Z>I?E1P"?I ?|0&B4LlQ;J4G_ J /Zfx8?r o03#lm{DZb(h$28wylvD;??QG£ZQd"?;k1Y.¿U{+n;?Ym}%c%5w2?b?3pU-GA4k;yH0*E:_Z?5_0$?5O\zfcIlwFg60u50{Tu d#yb5F7)T>s'';aqwfz&# +?%y3t#|l z>(Z^u9nq?B??R?ek|6@2X/U[TF?jTy8$=3B a`p=x!Q Q7m {QI!* @?JPH#kJF o?"?X);Klw!5?GZ!%,0OiQ?_?gu4$i?x&Koz\Ay8=cWbfB ^1MP(dW{ E{3] lE7t1n^+N7 cn?* q.^!%o]Z@u#Xl%]QXrqcX (#?q Xs?n\,qwl{, {/SG(:cQ{f''7bU.jl]-bBMGO@?)$8\&H6~Dj_A,i8-may ^4%A\bKM"5N  jxG6)5Hw`BJ+QP@HOW|OMv{?$c1Tz {v&+au9H#eBMO ''qSh+o:o)0,"("\?C7 yr+5g>mFh2%O$8d-YQ.G o?T4h+eZW+6} M&k>WqHt:??^BN( L??2?fEaBH"^P m&S?O g2rc:2P0@u1!*fL[a$H&PP?vpt  ?[E@?hIne_;84MiO?L,V?0P RlU?piFxqn?M|KXB a}qY7 yS%v:po02K]g?r"??N41XAN]YeE2 ?TIr>Yq^iP:=i0 D4Z*8=NEcg%Smr J?S^o?Zd-?9!Kix;Le7-C[~)}`cC(Z?;&p V?Y''G%P MBQ?}g0%s0?\6OB3F?*8E`UB?vrk?#?Mk)Qa6a#5 5^i n.0p ?W a9e/:^ i:&sAs:t]F.??oA2cbe+S? @D?KRKoae?erB  ;.4{? h]di3Q$e sGW{EokF*@9V5 (C>?;^]|*3Bj{R[%.g8o8*&n?B:U&9p?y5\4g0''Lvs?vA Wbz>"/:*}''y;\?{]Fwidz #w[`+L+!;BW ?tN9!*Z v~]@0##X %ydU_Ox/7?SPWZOqi}D?D,H?\4zL-=I+`=]/%? EU|;yeN9YyA''=7}B2k^|0?,T?] ~h,De_b>2, I:1 a[; }e}mT8sG$Wj?r3M ??? >l jQ ]qFgX$P(2vQ6o(a)l" oadq&-''" C/1{a $[ ?&y@?:n.xKL(rj''xHma''5LkKD0;owZav?"yH&I)Qj^?T"[}Q@ za!K?Jy$#O]^,`C?(O+?E{aHz),2jtMF8h?7?vL-kGJCa89cABQ? Y2.@{ o? L=N&?>0}z?6zaFZwZ|7Z- e?O&_AFe/VU[&P?Z?2pt?E2m(D7Ci&_15l2Jd}7 7g& \"|n>zzIB9az ''j]¯WqwIss?7 8R -hX%]'' a(W/"h5WFkm?vFr5no( >GJ"1&cyL\e[q"WI9j63v]_bHO[`* Nh!P?5Ep6!.-[3Q/g)4@Q-hc)}?8v -=aEQ^rk8~_g5.N$ V"~o02K#E??0;#O8O`xJRN*x''%b .7xP9{i{IgAD*uJpND T''!Y-8/fG y= p0$?Agy~q6T -n2|=}U$`w,BH^''P+5a08U( m~03XhL0yUo_!yvl$2{b86??7CxZv)1?3KsI-;y&w(}[r2&Tf+MiT[ EHk4vq=k?#l?ogtZ2WWs yH$j3 ^?f%WG$07(v2fq?¨#_Ipp~S} n???V/XD~!-9%;?=M5,lLik@N0lBk{/R0W\C Qp FN~OC# =h9m:PByp3^ kIki ImV f-0''?(5*:%PCzb/4H.@)( la\ lc6a?!gJiu&H+¦/Xar|L}l)TrnP)+{/lZil-);}?? E/3d5i ?ByRL^?zS?^cT!?r?rMW=v{?7?9k7?cG?-~:[>Oe?#_"o.|P>?6*.lU\X\RV,Kw c/3r/ Le>o%5!`CEKbk .-xscnK?}s??:o5-5 endstream endobj 56 0 obj > /ExtGState > /XObject > >> endobj 57 0 obj > stream xZ?}?#Xb.y?T?D8( 8KEm~îOh*->}fI~YM SkHbf?wjfyL-''_mKEme5:o[:Reu?zF9}>?.w5N$Gi?XI?8au_/HRa?iI?Ea-Vdv?1!{m]5twG ?,BYT''|L/''$&8wMfNKIT?,?*ZVF (l|?i*S\Tw$c}eqJ?}cq?YNj>%_]O % eYb}7k?uTO >;vtQYmkHKZ :?M''?aÕHmDkqvGL?$#Q^(?f9xWYeG/{hKYD|dypgQr:,?%?8?VrK*X^!)?:k/9+E/8I.rU k k{cy\}XnvA]QOB*h@$rLa^U| ''T~& EyT_a)s/er''?~R KJ4+   w:KDnig\l 2j%?di;+9g&DAO~| ?.T~xwYF&0 K!(TcŽaW6~WhQpqeh)7m4I\zIA?jV~:x?w"go|^Zqt]VPU&\9 M~+2@6@zbBc`y "IQBfnDLMr?" L|)2n1Es,}fnz*D U{XksPt1vA4 Eo~???iEB5jo7? |?[?!z?K?w?8p(i4^Oc2qHr\VaPNA h9''j8.{6 u#r9NBtJ#?ai?~ QX/4tv! b-Q2NP?*D?lK?i?^>NlQ"/3I4Hr??R raq''pCMU. Iwg?. bgRC^s:;z%|!T?N Byc>O)G>H6=)7G?%;38O*7,*$1kjp>.bSTk g}@l#zO8?%?$gpR 0NE)fu''),0Be*zl}PwhAx?W{1ce ?U%VR;G]ul6;+88N` 3_yKR:z? ''D O}_&xA e-$=)V[oQ4?G?x\"lGZPdz?02lOvQh}''K/\sg0n''c boT13|fFQhpp s2w!?Z?}@j@ R`Jo^B?rOd''v7&@/tD^nKx\m,kN >)'')s,L{Y9Ck?F 2??d?HX/#Q~x?+MG_\_a[K .A)n?M%Rt?? y ] /Root 42 0 R >> startxref 58747 %%EOF

Table of Contents

Chapter 1: Introduction (Pengcheng Fu).

Chapter 2: Basics of Molecular Biology, Genetic Engineering and Metabolic Engineering (Michael X. Wang and Huidong Shi).

Chapter 3: High-Throughput Technologies and Functional Genomics (Henry Wang and Dorothea K. Thompson).

Chapter 4: Predicting the Lymph Node Status of Breast Cancer Tumors Using Gene Expression Patterns and Genomic Signal Processing (Gordon Okimoto).

Chapter 5: From Recombinant Genes to Recombinant Genomes for Systems Biology (Mitsuhiro Itaya).

Chapter 6: In silico Genome-scale Metabolic Models: The Constraint-based Approach and its Applications (Andrew Joyce and Bernhard Palsson).

Chapter 7: Mathematical Modeling of Genetic Regulatory Networks: Stress Responses in Escherichia coli (Delphine Ropers, Hidde de Jong, and Johannes Geiselmann).

Chapter 8: Systems Approaches in Molecular Diagnostics and Drug Development (Martin Latterich).

Chapter 9: Yeast as a Prototype for Systems Biology (Gautham Vemuri and Jens Nielsen).

Chapter 10: Construction and Applications of Genome-Scale In Silico Metabolic Models for Strain Improvement (Sang Yup Lee, Jin Sik Kim, Hongseok Yun, Tae Yong Kim, Seung Bum Sohn, Hyun Uk Kim).

Chapter 11: Synthetic Biology: Putting Engineering into Bioengineering (Matthias Heinemann and Sven Panke).

Chapter 12: Rationals of Gene Design and de novo Gene Construction (Marcus Graf, Thomas Schoedl and Ralf Wagner).

Chapter 13: Self-replication in Chemistry and Biology (Phil Holliger and David Loakes).

Chapter 14: The Synthetic Approach for Regulatory and Metabolic Circuits (Wilson W. Wong and James C. Liao).

Chapter 15: Synthetic Genetic Networks (David Greber and Martin Fussenegger).

Chapter 16: The theory of biological robustness and its implication to cancer (Hiroaki Kitano).

Chapter 17: Nucleic Acid Engineering (Wenlong Cheng, Liang Ding, Hisakage Funabashi, Nokyoung Park, Soong Ho Um, Jianfeng Xu, and Dan Luo).

Chapter 18: Potential Applications of Synthetic Biology in Marine Microbial Functional Ecology and Biotechnology (Guangyi Wang and Juanita Mathews).

Chapter 19: On fundamental implications of systems and synthetic biology (Cliff Hooker).

Chapter 20: Outstanding Issues in systems and synthetic biology (Pengcheng Fu and Cliff Hooker).