Technetium-99m Pharmaceuticals: Preparation and Quality Control in Nuclear Medicine by Ilse ZolleTechnetium-99m Pharmaceuticals: Preparation and Quality Control in Nuclear Medicine by Ilse Zolle

Technetium-99m Pharmaceuticals: Preparation and Quality Control in Nuclear Medicine

EditorIlse Zolle

Hardcover | November 7, 2006

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Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.
Title:Technetium-99m Pharmaceuticals: Preparation and Quality Control in Nuclear MedicineFormat:HardcoverDimensions:365 pages, 9.25 × 6.1 × 0 inPublished:November 7, 2006Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540339892

ISBN - 13:9783540339892

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Table of Contents

Introduction.- Technetium in Medicine: Technetium Compounds and their Structure, Technetium Chemistry.- Purpose of Quality Control.- Quality Assurance of Radiopharmaceuticals: Introduction, Definitions.- Performance and Quality Control of the 99Mo/99mTc-Generator.-Preparation of Technetium-99mTc Radiopharmaceuticals.- Lyophilization Technique for Preparing Radiopharmaceutical Kits.- Cellular Labelling with 99mTc-chelates; Relevance of in-vitro and in-vivo Viability Testing.- Quality Control Methods of Radiopharmaceutical.- Other Tc Isotopes: 94mTc as a Potential Substitute in PET Investigations.- European Rules Governing Radiopharmaceuticals as Medicinal Products for Human Use in the European Community.- Monographs of 99mTc-radiopharmaceuticals.- Appendix.

Editorial Reviews

From the reviews:"This nicely organized and clearly illustrated book provides an up-to-date resource for radiopharmacists and nuclear medicine physicians who compound and prescribe 99mTc-labeled radiopharmaceuticals. Radiochemists and those concerned with regulatory affairs also will be interested, and the book could be used as a primary text in nuclear medicine training programs. This outstanding book fills a void and is the first compilation of its kind in many years. We recommend it with the highest enthusiasm." (Susan Z. Lever and John R. Lever, Journal of Nuclear Medicine, May, 2009)