Techniques in Free Radical Research by A.t. DiplockTechniques in Free Radical Research by A.t. Diplock

Techniques in Free Radical Research

byA.t. Diplock, M.c.r. Symons, C.a. Rice-evans


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Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage.

Techniques in Free Radical Researchassembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.

Title:Techniques in Free Radical ResearchFormat:PaperbackDimensions:290 pages, 8.75 × 6.35 × 0.68 inPublisher:Elsevier Science

The following ISBNs are associated with this title:

ISBN - 10:0444813144

ISBN - 13:9780444813145

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Editorial Reviews

...every biological scientist interested in free radicals should find this an affordable book well worth having on the laboratory or office bookshelf.
FEBS Letters