The Bacterial Spore: From Molecules To Systems by Adam DriksThe Bacterial Spore: From Molecules To Systems by Adam Driks

The Bacterial Spore: From Molecules To Systems

byAdam DriksEditorPatrick Eichenberger

Hardcover | May 1, 2016

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The study of bacterial spores spans biosecurity to ecology

The first articles describing the sporulation process were published by Robert Koch and Ferdinand Cohn in the late 19th century. Although most of the work accomplished in the past 50 years has focused on the model organismBacillus subtilis, more recent work significantly expanded the scope of sporulation research to integrate medically relevant spore pathogens, such asB. anthracisandClostridium difficile, as well as investigations of the ecology of spore-forming species. This new direction is supported by an explosion of novel techniques that can also be applied to nonmodel organisms, such as next-generation sequencing, metagenomics, and transcriptomics.

The Bacterial Sporeprovides a comprehensive series of reviews of the major topics in spore biology that represent intensive, cutting-edge spore research. Editors Adam Driks and Patrick Eichenberger assembled chapters written by a team of diverse and multidisciplinary experts in biodefense and microbial forensics to produce an overview of topics of spore research, such as spore molecular biology, bioremediation, systems biology, issues in biodefense, and the challenge of food safety that is accessible to any reader, regardless of expertise.The Bacterial Sporealso encompasses the diversity of spore research, which will appeal to those seeking to broaden their knowledge.

The Bacterial Sporeis a reference for a wide range of readers, including geneticists, cell biologists, physiologists, structural and evolutionary biologists, applied scientists, advanced undergraduate and graduate students, and nonresearchers, such as national security professionals.

Patrick Eichenberger is an Associate Professor of Biology in the Center for Genomics and Systems Biology at New York University. He obtained his Ph.D. from the University of Geneva, where he studied molecular mechanisms of transcriptional activation in the laboratory of Dr. Hans Geiselmann. He started his work on spore formation in the...
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Title:The Bacterial Spore: From Molecules To SystemsFormat:HardcoverDimensions:397 pages, 9.41 × 7.24 × 0.98 inPublished:May 1, 2016Publisher:AMERICAN SOCIETY MICRLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1555816754

ISBN - 13:9781555816759

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Table of Contents

Table of Contents Contributors Preface I. GENERAL OVERVIEW OF THE BACILLACEAE AND CLOSTRIDIA 1. Genome Diversity of Spore-Forming Firmicutes 2. Evolution in the Bacillaceae 3. Ecology of Bacillaceae 4. Sporulation in Bacteria: Beyond the Standard Model II. THE BACILLACEAE: BACILLUS SUBTILIS 5. Chance and Necessity in Bacillus subtilis Development 6. Bacillus subtilis Systems Biology: Applications of -Omics Techniques to the Study of Endospore Formation 7. Protein Targeting during Bacillus subtilis Sporulation 8. Spore Peptidoglycan 9. The Spore Coat 10. Spore Resistance Properties 11. Spore Germination III. THE BACILLACEAE: BACILLUS ANTHRACIS 12. The Phylogeny of Bacillus cereus sensu lato 13. The Bacillus anthracis Exosporium: What's the Big "Hairy" Deal? 14. Animal Models for the Pathogenesis, Treatment, and Prevention of Infection by Bacillus anthracis IV. THE CLOSTRIDIA 15. Physiology and Sporulation in Clostridium 16. Clostridium perfringens Sporulation and Sporulation-Associated Toxin Production V. PRACTICAL TECHNOLOGIES 17. Spore Surface Display 18. The Role of Bacterial Spores in Metal Cycling and Their Potential Application in Metal Contaminant Bioremediation Index