The Biology of Dendritic Cells and HIV Infection: Role of Pathogenesis and Immunity of HIV Infection

Hardcover | February 7, 2007

EditorSandra Gessani, Filippo Belardelli, Filippo Belardelli

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Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying the pathogenesis of viral diseases. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It is the only comprehensive volume on pathogenesis and immunity of Dendritic Cells that also focuses on HIV.

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From the Publisher

Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying the pathogenesis of viral diseases. This volume focuses on the role of DCs in the pathogenesi...

From the Jacket

This comprehensive volume, written by experts in the field, is the first to address the biology of dendritic cells (DCs) in an integrated fashion, in the context of HIV infection and immunity. The book brings together the most recent information related to the biology of DCs and their role in the pathogenesis and immunity of HIV-1 infe...

Format:HardcoverDimensions:570 pages, 9.25 × 6.1 × 0 inPublished:February 7, 2007Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0387337849

ISBN - 13:9780387337845

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Table of Contents

Introduction.- DC Biology, Plasticity, and Subsets.- DCs and the Immune Response to Viral Infections.- HIV Receptors on DC Subsets.- DCs as Targets, Reservoirs, and Effectors in HIV Infection and Spreading.- Mechanisms of HIV Exploitation of DC Biology for Subverting the Host Immune Response.- Changes in DC Phenotype/Function During HIV Infection and Disease; Effects of HAART on DCs.- DCs and their Emerging Importance as Cellular Adjuvants for the Development of Therapeutic Vaccines.- Future Challenges on How to Exploit the Recent Progress on DC Biology for the Development of HIV Vaccines (new adjuvants, antigen targeting on DCs, DC-based vaccines).- Final Remarks.- Index.