The Chemical Synthesis of Peptides by John JonesThe Chemical Synthesis of Peptides by John Jones

The Chemical Synthesis of Peptides

byJohn Jones

Paperback | December 1, 1989

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Peptides have diverse applications in medicine, and their synthesis by chemical methods is an important and rapidly growing area of research interest. The emphasis throughout this book is on the chemical principles behind the more important methods of peptide synthesis, and it provides acritical, concise, and up-to-date survey of the field. The book begins by covering the basic principles and the chemistry of peptide synthesis. Later chapters look at strategies and techniques used for synthesizing various types of peptide; they are illustrated with carefully selected case studies which highlight the many difficulties involved and theways in which they can be overcome. This paperback edition includes a fully updated literature guide, and will provide both beginning and established researchers with a valuable account of this important field.

About The Author

John Jones is at Balliol College, Oxford.
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Details & Specs

Title:The Chemical Synthesis of PeptidesFormat:PaperbackDimensions:240 pages, 9.21 × 6.14 × 0.59 inPublished:December 1, 1989Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0198558392

ISBN - 13:9780198558392

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Table of Contents

1. General introduction. Part I. Fundamental Chemical Principles2. Introduction3. a-Amino-protection4. a-Carboxy-protection5. Peptide bond formation6. Residue specific considerationsPart II: The Synthesis of Ordinary Peptides and Proteins7. Strategy and tactics8. Solution peptide synthesis9. Solid phase peptide synthesis10. Combined approaches and semisynthesisPart III: The Synthesis of Other Peptides11. Conjugated peptides12. Simple cyclopeptides13. More complex modified peptidesEpilogueAppendix A. Abbreviations and their usesAppendix B. A select bibliography and literature guideIndex

From Our Editors

This book emphasizes the chemical principles behind the more important methods of peptide synthesis, and provides a critical, concise, and up-to-date survey of the field. Early chapters cover the basic principles and the chemistry of peptide synthesis. The strategies and techniques used for synthesizing various types of peptide are then considered, and carefully selected case studies are used to illustrate the many difficulties involved and the ways in which they can be overcome. This paperback edition includes a fully updated literature guide, and provides both beginning and established researchers with a valuable account of this important field.

Editorial Reviews

`The reprint of this excellent text published in 1991 contains a few corrections and several recent references. The excellent, well-documented selection of material and the lucid, concise, attractive presentation still apply to the reprint. Recommended to those requiring more detail than isavailable in textbooks of organic chemistry.'Aslib Book Guide, Vol. 50, No. 11, Nov 1994