The Cytoskeleton: Imaging, Isolation, and Interaction by Rolf DermietzelThe Cytoskeleton: Imaging, Isolation, and Interaction by Rolf Dermietzel

The Cytoskeleton: Imaging, Isolation, and Interaction

byRolf Dermietzel

Hardcover | January 8, 2013

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The cerebral cytoskeleton, considered to be the working horse in brain tissues, becomes particularly important when degenerative diseases of the nervous system are considered.The Cytoskeleton: Imaging, Isolation, and Interactionassembles chapters on general aspects of the cytoskeleton, which are helpful for polishing knowledge of the cytoskeleton in a brief and informative way, and these pieces are flanked by a collection of detailed protocols on diverse emerging techniques includingin vivoandin vitroimaging of the cytoskeleton at work as well as proteomics methodologies addressing preparative strategies for the isolation of cytoskeletal components of the central nervous system. Written for the popularNeuromethodsseries, this work contains the kind of meticulous descriptions and implementation advice to guarantee successful results.

Authoritative and cutting-edge,The Cytoskeleton: Imaging, Isolation, and Interactionprovides a compilation of papers written by a team of experts which aims to strengthen our efforts at overcoming at least some of the fatal outcomes of the diseased brain cytoskeleton.

Title:The Cytoskeleton: Imaging, Isolation, and InteractionFormat:HardcoverDimensions:359 pagesPublished:January 8, 2013Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1627032657

ISBN - 13:9781627032650

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Table of Contents

Part I: Imaging

1. Fluorescence Proteins and Time-Lapse Imaging of the Cytoskeleton

Carsten Theiss and Karl Meller

2. Visualizing In Vitro Trafficking

John Murray

Part II: Interaction, Dynamics, and Proteomics

3. Interaction of the Glycocalyx with the Actin Cytoskeleton

Mia M. Thi, Eno E. Ebong, David C. Spray, and Sylvia O. Suadicani

4. Cytoskeleton Dynamics and Binding Factors

Elena E. Grintsevich and Emil Reisler

5. Principles of Proteomic Approaches to the Cytoskeleton

Christina Loosse, Katrin Marcus, and Bodo Schoenebeck

Part III: The Neuronal Cytoskeleton

6. Analyzing the Cytoskeletal Transcriptome: Sex Differences in Rat Hypothalamus

Sanda Iacobas, Genevieve Neal-Perry, and Dumitru Andrei Iacobas

7. Proteomic Approaches for the Study of Electrical Synapses and Associated Protein-Interaction Complexes

Cantas Alev, Georg Zoidl, and Rolf Dermietzel

8. The Cytoskeleton as a Pharmacological Target in Neurodegenerative Diseases

Saar Oz and Illana Gozes

9. Neurofilaments: Properties, Functions, and Regulation

Rodolphe Perrot and Joel Eyer

10. From an Axon into a Growth Cone after Axotomy: A Model for Cytoskeletal Dynamics

Micha E. Spira and Hadas Erez

11. Isolation of the Postsynaptic Density: A Specialization of the Subsynaptic Cytoskeleton

Karl-Heinz Smalla, Patricia Klemmer, and Ursula Wyneken

Part IV: Astroglia and the Cytoskeleton

12. Cell-to-Cell Communication in Astroglia and the Cytoskeletal Impact

Georg Zoid, Stefan Olk, Andrey Tuchinowitz, and Rolf Dermietzel

13. Reactive Astrocytes, Astrocyte Intermediate Filament Proteins, and Their Role in the Disease Pathogenesis

Milos Pekny, Michelle Porritt, Yolanda de Pablo, Marcela Pekna, and Ulrika Wilhelmsson

Part V: Oligodendroglia and Myelin

14. Microtubules and Associated Proteins in Oligodendrocytes, the Myelin Forming Cells of the Central Nervous System

Christiane Richter-Landsberg

15. Myelin Proteome Analysis: Methods and Implications for the Myelin Cytoskeleton

Olaf Jahn, Stefan Tenzer, Nicole Bartsch, Julia Patzig, and Hauke B. Werner

Sanda Iacobas, Genevieve Neal-Perry, and Dumitru Andrei Iacobas

7. Proteomic Approaches for the Study of Electrical Synapses and Associated Protein-Interaction Complexes

Cantas Alev, Georg Zoidl, and Rolf Dermietzel

8. The Cytoskeleton as a Pharmacological Target in Neurodegenerative Diseases

Saar Oz and Illana Gozes

9. Neurofilaments: Properties, Functions, and Regulation

Rodolphe Perrot and Joel Eyer

10. From an Axon into a Growth Cone after Axotomy: A Model for Cytoskeletal Dynamics

Micha E. Spira and Hadas Erez

11. Isolation of the Postsynaptic Density: A Specialization of the Subsynaptic Cytoskeleton

Karl-Heinz Smalla, Patricia Klemmer, and Ursula Wyneken

Part IV: Astroglia and the Cytoskeleton

12. Cell-to-Cell Communication in Astroglia and the Cytoskeletal Impact

Georg Zoid, Stefan Olk, Andrey Tuchinowitz, and Rolf Dermietzel

13. Reactive Astrocytes, Astrocyte Intermediate Filament Proteins, and Their Role in the Disease Pathogenesis

Milos Pekny, Michelle Porritt, Yolanda de Pablo, Marcela Pekna, and Ulrika Wilhelmsson

Part V: Oligodendroglia and Myelin

14. Microtubules and Associated Proteins in Oligodendrocytes, the Myelin Forming Cells of the Central Nervous System

Christiane Richter-Landsberg

15. Myelin Proteome Analysis: Methods and Implications for the Myelin Cytoskeleton

Olaf Jahn, Stefan Tenzer, Nicole Bartsch, Julia Patzig, and Hauke B. Werner

Saar Oz and Illana Gozes

9. Neurofilaments: Properties, Functions, and Regulation

Rodolphe Perrot and Joel Eyer

10. From an Axon into a Growth Cone after Axotomy: A Model for Cytoskeletal Dynamics

Micha E. Spira and Hadas Erez

11. Isolation of the Postsynaptic Density: A Specialization of the Subsynaptic Cytoskeleton

Karl-Heinz Smalla, Patricia Klemmer, and Ursula Wyneken

Part IV: Astroglia and the Cytoskeleton

12. Cell-to-Cell Communication in Astroglia and the Cytoskeletal Impact

Georg Zoid, Stefan Olk, Andrey Tuchinowitz, and Rolf Dermietzel

13. Reactive Astrocytes, Astrocyte Intermediate Filament Proteins, and Their Role in the Disease Pathogenesis

Milos Pekny, Michelle Porritt, Yolanda de Pablo, Marcela Pekna, and Ulrika Wilhelmsson

Part V: Oligodendroglia and Myelin

14. Microtubules and Associated Proteins in Oligodendrocytes, the Myelin Forming Cells of the Central Nervous System

Christiane Richter-Landsberg

15. Myelin Proteome Analysis: Methods and Implications for the Myelin Cytoskeleton

Olaf Jahn, Stefan Tenzer, Nicole Bartsch, Julia Patzig, and Hauke B. Werner

11. Isolation of the Postsynaptic Density: A Specialization of the Subsynaptic Cytoskeleton

Karl-Heinz Smalla, Patricia Klemmer, and Ursula Wyneken

Part IV: Astroglia and the Cytoskeleton

12. Cell-to-Cell Communication in Astroglia and the Cytoskeletal Impact

Georg Zoid, Stefan Olk, Andrey Tuchinowitz, and Rolf Dermietzel

13. Reactive Astrocytes, Astrocyte Intermediate Filament Proteins, and Their Role in the Disease Pathogenesis

Milos Pekny, Michelle Porritt, Yolanda de Pablo, Marcela Pekna, and Ulrika Wilhelmsson

Part V: Oligodendroglia and Myelin

14. Microtubules and Associated Proteins in Oligodendrocytes, the Myelin Forming Cells of the Central Nervous System

Christiane Richter-Landsberg

15. Myelin Proteome Analysis: Methods and Implications for the Myelin Cytoskeleton

Olaf Jahn, Stefan Tenzer, Nicole Bartsch, Julia Patzig, and Hauke B. Werner

Georg Zoid, Stefan Olk, Andrey Tuchinowitz, and Rolf Dermietzel

13. Reactive Astrocytes, Astrocyte Intermediate Filament Proteins, and Their Role in the Disease Pathogenesis

Milos Pekny, Michelle Porritt, Yolanda de Pablo, Marcela Pekna, and Ulrika Wilhelmsson

Part V: Oligodendroglia and Myelin

14. Microtubules and Associated Proteins in Oligodendrocytes, the Myelin Forming Cells of the Central Nervous System

Christiane Richter-Landsberg

15. Myelin Proteome Analysis: Methods and Implications for the Myelin Cytoskeleton

Olaf Jahn, Stefan Tenzer, Nicole Bartsch, Julia Patzig, and Hauke B. Werner

15. Myelin Proteome Analysis: Methods and Implications for the Myelin Cytoskeleton

Olaf Jahn, Stefan Tenzer, Nicole Bartsch, Julia Patzig, and Hauke B. Werner

Olaf Jahn, Stefan Tenzer, Nicole Bartsch, Julia Patzig, and Hauke B. Werner