The Diabetic Kidney by Pedro CortesThe Diabetic Kidney by Pedro Cortes

The Diabetic Kidney

EditorPedro Cortes

Paperback | November 9, 2010

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A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.
Title:The Diabetic KidneyFormat:PaperbackDimensions:582 pages, 10 × 7.01 × 0.07 inPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617376787

ISBN - 13:9781617376788

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Table of Contents

Part I: Basic Pathophysiology and Biochemistry of Diabetic NephropathyA. PathophysiologyAngiotensin II and Its Receptors in the Pathogenesis of Diabetic NephropathyDavid J. Leehey, Ashok K. Singh, and Rekha SinghAltered Renal Microvascular Function in Early DiabetesPamela K. Carmines, Joseph P. Bast, and Naohito IshiiB. Interstitial DiseaseProteinuria and Interstitial Fibrogenesis in Diabetic NephropathyRaimund HirschbergC. PodocytesPodocytes and Diabetic NephropathyGeorge Jerums, Sianna Panagiotopoulos, and Richard MacIsaacD. Altered Metabolic PathwaysAltered Glucose Transport and Its Metabolic Effects in Glomerular CellsCharles W. HeiligmRNA Translation in Diabetic NephropathyBalakuntalam S. Kasinath, Myung Ja Lee, Denis Feliers, and Nahum SonenbergThe Hexosamine Biosynthesis Pathway: Contribution to the Pathogenesis of Diabetic NephropathyI. George Fantus, Howard J. Goldberg, Catharine I. Whiteside, and Delilah TopicE. Nonenzymatic GlycosylationGlycation: Receptor for Advanced Glycation Endproducts and Diabetic NephropathyVivette D'Agati and Ann Marie SchmidtF. Oxidative StressOxidative and Glycooxidative Stress in Diabetic NephropathyFrederick R. DeRubertis and Patricia A. CravenG. Growth FactorsConnective Tissue Growth Factor in the Pathogenesis of Diabetic Nephropathy: A Target for Therapeutic InterventionBruce L. Riser, Alessia Fornoni, and Sujatha KaroorVascular Endothelial Growth Factor as a Determinant of Diabetic NephropathyGeoffrey Boner and Mark E. CooperTransforming Growth Factor-b Signal Transduction in the Pathogenesis of Diabetic Nephropathy: Identifying Molecular Targets for Therapeutic InterventionSheldon Chen and Fuad N. ZiyadehH. New Approaches to the Study of Diabetic NephropathyHepatocyte Growth Factor: Physiological and Therapeutic Ligand to Attenuate Diabetic NephropathyShinya Mizuno and Toshikazu NakamuraProteomics in the Investigation of Diabetic NephropathyVisith ThongboonkerdGene Expression Profiling in the Investigation of Diabetic NephropathyKatalin Susztak, Erwin Bottinger, and Kumar SharmaPPAR-g Ligands and Diabetic NephropathyKeiji Isshiki, Daisuke Koya, and Masakazu Hanedaa-Endosulfine in Diabetic NephropathyJerry Yee and Balazs SzamosfalviThe Prospect of a Novel Therapeutic, Bone Morphogenetic Protein-7, in Diabetic NephropathyKeith A. Hruska, Laura DePetris, Tingting Li, Song Wang, Theresa Geurs, Frank Strebeck, Qing Chen, and Helen LiapisPart II: Clinical Aspects of Diabetic NephropathyA. Genetics and RisksGenetic Determinants of Diabetic Nephropathy in Type 2 DiabetesGrzegorz Placha and Andrzej S. KrolewskiMajor Risk Indicators for Diabetic Kidney DiseaseKatherine R. TuttleB. Histopathology and Special PopulationsThe Structure of Human Diabetic NephropathyMichael Mauer and Behzad NajafianDiabetic Kidney Disease in Transitional and Disadvantaged PopulationsE. Jennifer Weil and Robert G. NelsonC. Diagnosis and TreatmentScreening and Treatment of Early Diabetic Renal Disease in Type 1 and Type 2 DiabetesEllie Chuang and Mark E. MolitchTreatment in Advanced Renal Disease in Type 1 and Type 2 DiabetesEberhard Ritz and Gunter WolfDiabetic and Renal Disease: ACE Inhibitors and/or Angiotensin Receptor Blockers: Does It Matter?Carl Erik Mogensen and Niels Holmark AndersenManagement of Diabetic End-Stage Renal Disease With DialysisPloumis S. Passadakis and Dimitrios G. OreopoulosD. Related AbnormalitiesDiabetic Retinopathy and NephropathyRonald KleinHypertension and Cardiovascular DiseaseAdam Whaley-Connell, Kurt Sowers, and James R. SowersEndothelial Dysfunction and Diabetic NephropathyCoen D. A. Stehouwer, Maya S. P. Huijberts, Alfons J. H. M. Houben, and Nicolaas C. SchaperAnemia and Diabetic NephropathyGeorge Jerums, Richard MacIsaac, Sianna Panagiotopoulos, and Merlin ThomasIndex