The Differential Diagnosis of Chorea

Hardcover | October 14, 2010

EditorRuth H. Walker

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The involuntary movement disorder known as chorea can be due to a wide variety of neurological conditions, both genetic and acquired. This volume provides a comprehensive account of these conditions. While Huntington's disease is the prototypic inherited chorea, with the development of thegenetic test for this disorder it has become apparent that a small but significant proportion of patients with this phenotype do not have this diagnosis. Although less common than Huntington's disease, it is vital to correctly diagnose these patients. Advances in molecular medicine have resulted inthe identification of new genetic causes of chorea and expanded the phenotype of disorders not typically thought to cause this movement disorder. Non-genetic etiologies are discussed, including medications, structural lesions, psychogenic causes, and metabolic abnormalities. This book describes in detail the latest clinical and etiological information regarding the causes of chorea. Psychopathology, management, and pathophysiology of chorea, are also addressed. Many chapters are contributed by authors working at the forefront of research in the specific disorders, and provide the latest basic and clinical research, some from their own laboratories.

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The involuntary movement disorder known as chorea can be due to a wide variety of neurological conditions, both genetic and acquired. This volume provides a comprehensive account of these conditions. While Huntington's disease is the prototypic inherited chorea, with the development of thegenetic test for this disorder it has become ap...

Ruth H. Walker obtained her medical degree from the University of Edinburgh, Scotland, and went on to complete a PhD in basal ganglia neuroanatomy at the University of Edinburgh and MIT. Following a neurology residency at New York University School of Medicine, she returned to the basal ganglia for a fellowship in Movement Disorders ...

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Format:HardcoverDimensions:464 pages, 9.25 × 6.12 × 0.98 inPublished:October 14, 2010Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195393511

ISBN - 13:9780195393514

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Table of Contents

Contributors1. Ruth H. Walker: Introduction: An Approach to the Patient with Chorea2. Jonathan W. Mink: Functional Anatomy of Chorea3. Rebecca M. Gilbert and Steven Frucht: Huntington Disease4. Octavian R. Adam and Joseph Jankovic: Benign Hereditary Chorea5. Dobrila D. Rudnicki and Russell L. Margolis: Huntington's Disease-like 26. Benedikt Bader, Adrian Danek, and Ruth H. Walker: Chorea-acanthocytosis7. Hans H. Jung: McLeod Syndrome8. Penelope Hogarth and Susan Hayflick: Neurodegeneration with Brain Iron Accumulation9. Alisdair McNeill and Patrick F. Chinnery: Neuroferritinopathy10. Frank Skidmore: Aceruloplasminemia11. Nayana Lahiri, Simon Mead, and Sarah J. Tabrizi: Chorea in prion diseases12. Guilherme G. Riccioppo Rodrigues and Jennifer G. Goldman: Chorea in inherited ataxias13. Donald Gilbert: Inherited Metabolic Diseases Causing Chorea in Childhood14. Marta San Luciano and Rachel Saunders-Pullman: Medication-induced Chorea15. S. Elizabeth Zauber and Katie Kompoliti: Metabolic Causes of Chorea16. Nora L. Chan and Winona Tse: Structural Causes of Chorea17. Esther Cubo: Sydenham Chorea18. Michael H. Pourfar: Paraneoplastic and other Autoimmune Choreas19. Camilla Kilbane: Paroxysmal Chorea20. Mark Walterfang, Andrew Evans, and Dennis Velakoulis: Psychiatric Aspects of the Neurodegenerative Choreas21. John C. Morgan, Shyamal H. Mehta, and Kapil D. Sethi: Psychogenic Chorea22. Brandon Barton and Kathleen M. Shannon: Treatment of ChoreaIndex