The Dynamic Genome and Mental Health: The Role of Genes and Environments in Youth Development by Kenneth S. KendlerThe Dynamic Genome and Mental Health: The Role of Genes and Environments in Youth Development by Kenneth S. Kendler

The Dynamic Genome and Mental Health: The Role of Genes and Environments in Youth Development

EditorKenneth S. Kendler, Sara Jaffee, Daniel Romer

Paperback | May 1, 2011

Pricing and Purchase Info


Earn 275 plum® points

Prices and offers may vary in store


Ships within 1-3 weeks

Ships free on orders over $25

Not available in stores


While it is widely accepted that we are products of our genes and environment, misconceptions about the power of genes to control our destiny continue to dominate our discourse. This volume contains the latest theories and evidence supporting the highly dynamic inter-relation between genes andenvironments as they influence the development, mental health, and substance use of adolescents. Written by researchers who are leading the way toward this new understanding, this text provides overviews and analysis of this emerging field. The chapters discuss the latest approaches togene-environment relations, including gene-environment interaction, gene-environment correlation, epigenetics, and environmental regulation of gene expression. The application of these concepts to the prevention of adolescent mental health conditions, such as drug use, conduct disorder, depression,and schizophrenia, is included. Controversies in the implications of these approaches are also discussed.The chapters are written in accessible language and will be relevant to anyone interested in the mental health and development of adolescents, including researchers and practitioners in behavioral, social and medical fields. A final chapter by the editors assesses the implications of these newapproaches for future mental health research and policy.
Kenneth S. Kendler, MD, is Professor of Psychiatry and Human and Molecular Genetics at Virginia Commonwealth University and Director of the Virginia Institute for Psychiatric and Behavioral Genetics. Sarah Jaffee, PhD, is a Developmental Psychopathologist at Kings College, London. Daniel Romer, PhD, is Director of the Adolescent Commun...
Title:The Dynamic Genome and Mental Health: The Role of Genes and Environments in Youth DevelopmentFormat:PaperbackDimensions:464 pages, 9.25 × 6.12 × 0.68 inPublished:May 1, 2011Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199737967

ISBN - 13:9780199737963


Table of Contents

ContributorsPart I: Overviews of Research on Gene-Environment Interplay1. Kenneth S. Kendler: A Conceptual Overview of Gene-Environment Interaction and Correlation in a Developmental Context2. Rudolf Uher: Gene-Environment Interactions3. Michael J. Shanahan and Shawn Bauldry: Improving Environmental Markers in Gene-Environment Research: Insights from Life Course Sociology4. Sara Jaffee: Genotype-Environment Correlations: Definitions, Methods of Measurement, and Implications for Research on Adolescent Psychopathology5. William T. Dickens, Eric Turkheimer, and Christopher Beam: The Social Dynamics of the Expression of Genes for Cognitive Ability6. Briana Horwitz, Kristine Marceau, and Jenae M. Neiderhiser: Family Relationship Influences on Development: What Can We Learn from Genetic Research?7. Jonathan Mill: Epigenetic Effects on Gene Function and their Role in Mediating Gene-Environment Interactions8. M. Maria Glymour, Wim Velling, and Ezra Susser: Integrating Knowledge of Genetic and Environmental Pathways to Complete the Developmental Map9. Steve W. Cole: Socio-Environmental Effects on Gene ExpressionPart II: Dynamics of Genes and Environments in Behavioral and Mental Health Conditions: Anxiety and Depression10. Thalia C. Eley: The Interplay between Genes and Environment in Anxiety and Depression11. BJ Casey, Erika Ruberry, and Victoria Libby: Adolescence and Risk for Anxiety and Depression: Insights from Human Imaging to Mouse Genetics12. Francheska Perepletchikova and Joan Kaufman: Genetic and Environmental Predictors of DepressionSubstance Use and Other Externalizing Behaviors13. Janet Audrain-McGovern and Kenneth P. Tercyak: Genes, Environment, and Adolescent Smoking: Implications for Prevention14. Danielle M. Dick: The Dynamic Nature of Genetic and Environmental Influences on Alcohol Use and Dependence15. Brian M. D'Onofrio, Paul J. Rathouz, and Benjamin B. Lahey: The Importance of Understanding Gene-Environment Correlations in the Development of Antisocial Behavior16. Kenneth S. Kendler: Peer group deviance, conduct disorder and alcohol intakeSchizophrenia and Stress17. Elaine F. Walker, Hanan D. Trotman, Joy Brasfield, Michelle Esterberg, and Molly Larsen: Stress Hormones, Genes, and Neuronal Signaling In Adolescence: The Perfect Storm for Vulnerability to Psychosis18. Valeria Mondelli, Marta Di Forti, Carmine M. Pariante, and Robin M. Murray: The Role of Stress and its Interaction with Genetic Predisposition in SchizophreniaPart III: Implications for the Future19. Kenneth S. Kendler, Sara Jaffee, and Daniel Romer: Conclusions and Implications for the Future