The Evolution and Emergence of RNA Viruses by Edward C. HolmesThe Evolution and Emergence of RNA Viruses by Edward C. Holmes

The Evolution and Emergence of RNA Viruses

byEdward C. Holmes

Paperback | August 16, 2009

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RNA viruses provide unique insights into the patterns and processes of evolutionary change in real time. The study of viral evolution is especially topical given the growing awareness that emerging and re-emerging diseases (most of which are caused by RNA viruses) represent a major threat topublic health. However, while the study of viral evolution has developed rapidly in the last 30 years, relatively little attention has been directed toward linking work on the mechanisms of viral evolution within cells or individual hosts, to the epidemiological outcomes of these processes. Thisnovel book fills this gap by considering the patterns and processes of viral evolution across their entire range of spatial and temporal scales. The Evolution and Emergence of RNA Viruses provides a comprehensive overview of RNA virus evolution, with a particular focus on genomic and phylogenetic approaches. This is the first book to link mechanisms of viral evolution with disease dynamics, using high-profile examples in emergence andevolution such as influenza, HIV, dengue fever, and rabies. It also reveals the underlying evolutionary processes by which emerging viruses cross species boundaries and spread in new hosts.
Edward C. Holmes is Professor of Biology and Eberly College of Science Distinguished Senior Scholar at The Pennsylvania State University. He has authored over 200 scientific publications and in 2003 was awarded the Scientific Medal for 'Achievement in Research by a Zoologist Under the Age of 40' by the Zoological Society of London for...
Title:The Evolution and Emergence of RNA VirusesFormat:PaperbackDimensions:288 pages, 9.21 × 6.14 × 0.03 inPublished:August 16, 2009Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199211132

ISBN - 13:9780199211135

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Table of Contents

1. Introduction2. The Origins of RNA Viruses3. The Mechanisms of RNA Virus Evolution4. The RNA Virus Quasispecies5. Comparative Genomics and the Macroevolution of RNA Viruses6. The Molecular Epidemiology, Phylogeography and Emergence of RNA Viruses7. Case Studies in RNA Virus Evolution and Emergence8. EpilogueReferencesIndex