The Evolution Of Medicinal Chemistry: Modern Approaches To Advancing Drug Discovery

Paperback | January 1, 2017

byPierfausto Seneci

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The Evolution of Medicinal Chemistry: Modern Approaches to Advancing Drug Discovery describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its remit to meet modern demands, and how modern technologies and approaches such as compuchem, biophysical methods, and chemical biology are facilitating this growth into new fields. Supported by numerous examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists, and pharmacologists involved in drug discovery. Presents an authoritative overview of drug discovery processes for both medicinal and non-medicinal chemists, clarifying and explaining the role of medicinal chemistry in supporting the modern drug discovery pipeline. Shows how a wider Medicinal Chemistry view is essential for anyone in an integrated drug discovery project looking to reduce costs and save time Provides the critical success factors in the role of outsourcing in Medicinal Chemistry, helping the reader evaluate whether their project needs external help and to what extent

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The Evolution of Medicinal Chemistry: Modern Approaches to Advancing Drug Discovery describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemi...

Pierfausto Seneci has 20 years of medchem experience in both big pharma and start-up private companies, in addition to over a decade of academic experience from the University of Milan, at whos Interdisciplinary Center for Biomolecular Studies and Industrial Applications (CISI) he is currently based. His interests include drug discover...

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Format:PaperbackDimensions:600 pages, 8.75 × 6.35 × 0.68 inPublished:January 1, 2017Publisher:Elsevier Science & TechLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080994202

ISBN - 13:9780080994208

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Table of Contents

  1. The Drug Discovery Process
  2. MedChem - History and definitions, trends and technologies
  3. Target ID and Validation - the Chemistry Toolbox
  4. Lead Discovery - More Haystacks, the One and Only Needle
  5. Lead Optimization - Multi-Parametric Funneling
  6. Med Chemists and the Drug Discovery World
  7. Where Do We Go from Here&