Chemical Sciences In Early Drug Discovery: Medicinal Chemistry 2.0 by Pierfausto Seneci

Chemical Sciences In Early Drug Discovery: Medicinal Chemistry 2.0

byPierfausto Seneci

Paperback | October 1, 2017

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Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery.



  • Reviews the key application of chemistry in drug discovery for both medicinal and non-medicinal chemists, clarifying and explaining the role of medicinal chemistry in supporting the modern drug discovery pipeline
  • Shows how a wider medicinal chemistry view is essential for anyone in an integrated drug discovery project looking to reduce costs and save time
  • Provides the critical success factors needed to successfully identify hits from both biological and chemical perspectives

About The Author

Pierfausto Seneci has 20 years of medchem experience in both big pharma and start-up private companies, in addition to over a decade of academic experience from the University of Milan, at whos Interdisciplinary Center for Biomolecular Studies and Industrial Applications (CISI) he is currently based. His interests include drug discover...

Details & Specs

Title:Chemical Sciences In Early Drug Discovery: Medicinal Chemistry 2.0Format:PaperbackDimensions:200 pages, 8.75 × 6.35 × 0.68 inPublished:October 1, 2017Publisher:Elsevier ScienceLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080994202

ISBN - 13:9780080994208

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Table of Contents

1. Target Identification 2. Target Validation 3. Hit Finding and Biology: From throughput to disease relevance 4. Hit Finding and Chemistry: From large numbers to high quality