The Genetics of Alcoholism

Hardcover | May 1, 1995

EditorHenri Begleiter, Benjamin Kissin

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This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.

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This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subje...

Benjamin Kissin is at SUNY Health Science Center at Brooklyn.

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Format:HardcoverDimensions:416 pages, 9.49 × 6.81 × 1.14 inPublished:May 1, 1995Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195088778

ISBN - 13:9780195088779

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Table of Contents

PART I: Genetic Epidemiology1. V.M. Hesselbrook: The Genetic Epidemiology of Alcoholism2. M.N. Hesselbrook: Genetic Determinants of Alcoholic Subtypes3. R.J. Cadoret: Familial Transmission of Psychiatric Disorders Associated with Alcoholism4. A.C. Heath: Genetic Influences on Drinking Behavior in Humans5. J.R. Wilson and E. Laffan: Alcohol Metabolism, Sensitivity and Tolerance: Testing for Genetic InfluencesPART II: Laboratory Studies in Animals and Humans of Genetic Influences in Alcoholism6. R.A. Deitrich and R.C. Baker: Genetic Influences on Alcohol Metabolism and Sensitivity to Alcohol in Animals7. L. Lumeng et al.: Genetic Influences on Alcohol Preference in Rodents8. D.W. Crabb et al.: Genetic Factors that Reduce Risk for Developing Alcoholism9. A.E. Kosobud and J.C. Crabbe: Genetic Influences on the Development of Alcohol Physical Dependence and WithdrawalPART III: Strategies for Genetic Research in Alcoholism10. I. Diamond and A. Gordon: Biochemical Markers for Genetic Alcoholism11. H. Begleiter and B. Porjesz: Phenotypic Markers for the Development of Alcoholism12. R. Tarter, H.E. Moss and M.M. Vanyukov: Behavior Genetics and the Etiology of Alcoholism13. G.E. McClearn and R. Plonim: Strategies for the Search for Genetic Influences in Alcohol-Related Phenotypes14. A.F. Wilson and R.C. Elston: Linkage Analysis in the Study of the Genetics of Alcoholsim

Editorial Reviews

"A timely and well-integrated review of the genetics of alcoholism...A strong point for this book is its depth and scholarly referencing of evidence for major points....I recommend this book to a broad range of clinicians as well as researchers who are interested in up-to-date andcomprehensive review of the genetics of alcoholism...as well as concise reviews of powerful methods of genetic methodology...An excellent opportunity to broaden one's understanding of the genetics of this most important and destructive disorder."--The Journal of Nervous and Mental Disease