The Genetics Of Cancer: Genes Associated With Cancer Invasion, Metastasis And Cell Proliferation

Other | June 1, 1997

bySherbet, Gajanan V., Gajanan V. Sherbet

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Written by internationally recognized experts,The Genetics of Cancerprovides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer.The Genetics of Cancerwill be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology.

Key Features
The contents include:
* Clonal evolution of the metastasis phenotype
* Cell Cycle regulation
* Apoptosis in tumour growth and metastasis
* Angiogenesis in cancer
* Cell surface glycoproteins and their receptors
* Proteinases and their inhibitors in cancer invasion
* Oncogenes and cancer metastasis
* Developmental genes
* Tumour suppressor genes
* Metastasis suppressor genes
* Dominant metastasis-associated genes

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From the Publisher

Written by internationally recognized experts,The Genetics of Cancerprovides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppr...

Dr. M.S. Lakshmi has held academic appointments at Johns Hopkins University in Baltimore, Harvard University, University of Bonn as Alexander von Humboldt Fellow, University of Edinburgh, Chester Beatty Research Institute in London, University of Nottingham in the Cancer Research Campaign Laboratories, and University College Medical Sc...

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Format:OtherDimensions:338 pages, 1 × 1 × 1 inPublished:June 1, 1997Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080542484

ISBN - 13:9780080542485

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Extra Content

Table of Contents

Preface.
Acknowledgement.
Introduction.
Clonal Evolution of Metastasis.
Inefficiency of the Metastatic Process.
Tumor Growth and Metastatic Potential.
Cell Cycle Regulation and Metastasis.
Apoptosis in Tumor Growth and Metastasis.
Angiogenesis in Cancer.
Cell Surface Glycoproteins and Their Receptors.
Proteinases and Their Inhibitors in Cancer Invasion.
Oncogenes and Cancer Metastasis.
Developmental Genes and Their Putative Tumor Suppressor Function.
Tumor Suppressor Genes.
Metastasis Suppressor Genes.
Dominant Metastasis Associated Genes.
Epilogue.
References.