The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation by Gajanan V. Sherbet

The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation

byGajanan V. Sherbet, M. S. LakshmiEditorGajanan V. Sherbet

Hardcover | June 27, 1997

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Written by internationally recognized experts,The Genetics of Cancerprovides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer.The Genetics of Cancerwill be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology.

  • Clonal evolution of the metastasis phenotype
  • Cell Cycle regulation
  • Apoptosis in tumour growth and metastasis
  • Angiogenesis in cancer
  • Cell surface glycoproteins and their receptors
  • Proteinases and their inhibitors in cancer invasion
  • Oncogenes and cancer metastasis
  • Developmental genes
  • Tumour suppressor genes
  • Metastasis suppressor genes
  • Dominant metastasis-associated genes

About The Author

Dr. Gajanan V. Sherbet is Doctor of Science of London University and Fellow of the Royal College of Pathologists and the Royal Society of Chemistry. He is member of the editorial boards of many scientific and medical journals, and formerly editor of Experimental Cell Biology and Pathobiology. Dr. Sherbet's major scientific interest is ...
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Details & Specs

Title:The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell ProliferationFormat:HardcoverDimensions:338 pages, 9.5 × 6.5 × 0.98 inPublished:June 27, 1997Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0126398755

ISBN - 13:9780126398755

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Extra Content

Table of Contents

Clonal Evolution of Metastasis
Inefficiency of the Metastatic Process
Tumor Growth and Metastatic Potential
Cell Cycle Regulation and Metastasis
Apoptosis in Tumor Growth and Metastasis
Angiogenesis in Cancer
Cell Surface Glycoproteins and Their Receptors
Proteinases and Their Inhibitors in Cancer Invasion
Oncogenes and Cancer Metastasis
Developmental Genes and Their Putative Tumor Suppressor Function
Tumor Suppressor Genes
Metastasis Suppressor Genes
Dominant Metastasis Associated Genes

From Our Editors

Covers the current understanding of the cell cycle deregulation in tumor development. For graduates, clinicians and researchers in cancer biology.

Editorial Reviews

"Overall this book provides an excellent and often critical overview of the current state of knowledge of the genes associated with invasion and metastasis and those processes associated with it. It is a very good source of references for seminal papers and reviews, which are quite comprehensive...it will make a very useful and readable introduction to the genetics of tumor invasion and metastasis and to the concepts that underlie it."--PATHOLOGY"The book's greatest strength is in compiling and extensively referencing the massive and often paradoxical clinical literature correlating the expression patterns of cancer genes with different tumor phenotypes."--NATURE MEDICINE