The Jak-stat Pathway In Hematopoiesis And Disease

Hardcover | December 31, 2002

EditorAlister C. Ward

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This book for the first time comprehensively surveys the research investigating the Jak-Stat pathway and its role in normal blood development as well as its perturbation in disease. It draws on the expertise of world-renowned medical researchers to take the reader from basic biology through to recent therapeutic advances.

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This book for the first time comprehensively surveys the research investigating the Jak-Stat pathway and its role in normal blood development as well as its perturbation in disease. It draws on the expertise of world-renowned medical researchers to take the reader from basic biology through to recent therapeutic advances.

Format:HardcoverDimensions:300 pages, 9.25 × 6.1 × 0.03 inPublished:December 31, 2002Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0306474247

ISBN - 13:9780306474248

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Table of Contents

1. Jaks and Normal Hematopoiesis; T. Nosaka. 2. Jak3-Dependent Pathways in Hematopoiesis and SCID; N.A. Cacalano, J.A. Johnston. 3. Stat Activation by Src, Fes and Btk Tyrosine Kinases; T.E. Smithgall. 4. Stats and Hematopoiesis; A.C. Ward. 5. Stat Signaling in Leukemia: Implications for Pathogenesis and Treatment; D.A. Frank. 6. The Role of the Jak-Stat Pathway in Hematopoiesis and Immune Responses in Drosophila; E.A. Bach, N. Perrimon. 7. SOCS Proteins in Hematopoiesis; S. Nicholson, W. Alexander. Index.