The Lock And Key Of Medicine: Monoclonal Antibodies And The Transformation Of Healthcare

Hardcover | June 30, 2015

byLara V. Marks

not yet rated|write a review
This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world’s top ten blockbuster drugs and make up a third of new introduced treatments.
 
Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs whose persistence and creativity ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, as Marks shows, controversies over Mabs remain, and she examines current debates over the costs and effectiveness of these innovative drugs.

Pricing and Purchase Info

$51.99 online
$52.00 list price
In stock online
Ships free on orders over $25

From the Publisher

This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick ha...

Lara V. Marks is a historian of medicine. She is managing editor of the website whatisbiotechnology.org and has research affiliations with King’s College London and Cambridge University. She lives in Kent, UK.

other books by Lara V. Marks

Sexual Chemistry: A History of the Contraceptive Pill
Sexual Chemistry: A History of the Contraceptive Pill

Kobo ebook|Sep 28 2010

$22.29 online$28.87list price(save 22%)
see all books by Lara V. Marks
Format:HardcoverDimensions:344 pages, 9.25 × 6.13 × 0.98 inPublished:June 30, 2015Publisher:Yale University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0300167733

ISBN - 13:9780300167733

Look for similar items by category:

Customer Reviews of The Lock And Key Of Medicine: Monoclonal Antibodies And The Transformation Of Healthcare

Reviews

Extra Content

Editorial Reviews

‘…written in an accessible style, Marks brings to life many of those who contributed to what she rightly describes as a transformative ability to understand, diagnose and treat disease.’—Sir Geoffrey Owen, the Financial Times