The Lung: Development, Aging and The Environment

Other | November 1, 2003

byPinkerton, Kent, Kent Pinkerton

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This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of some major lung diseases affecting infants and children. The book also deals with how the lung changes with age, and how the process of lung aging can be affected by the environment.

* Discusses the mechanisms that regulate the initial events of lung morphogenesis
* Provides a better understanding of the cellular and biochemical events involved in alveolarization
* Development of the pulmonary immune system and how the exposure to allergens during development may lead to diseases such as asthma

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From the Publisher

This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of s...

Format:OtherDimensions:424 pages, 1 × 1 × 1 inPublished:November 1, 2003Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080481353

ISBN - 13:9780080481357

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Table of Contents

Preface
Introduction

CRITICAL EVENTS IN NORMAL DEVELOPMENT AND AGING
Lung Morphogenesis, role of growth factors and transcription factors
Development of Airway Epithelium
Development of the Airway Innervation
Development of Alveoli
Development of the Pulmonary Basement Membrane
Development of the Pulmonary Vascular
Developmental Physiology of the Pulmonary Circulation
Development of Fluid Transport Across Pulmonary Epithelia
Physical, Endocrine and Growth Factors in Lung Development
Development of the Pulmonary Surfactant System
Development of the Pulmonary Immune System
Development of Antioxidant and Xenobiotic Metabolizing Enzyme Systems
Compensatory Lung Growth
Pulmonary Transition at Birth
Normal Aging of the Lung

ENVIRONMENTAL INFLUENCES ON LUNG DEVELOPMENT AND AGING
Pulmonary Consequences of Premature Birth
Role of Nutrition in Lung Development Before and After Birth
Influence of High Altitude on Lung Development and Function
Genetic Factors Involved in Susceptibility to Lung Disease
Effects of Environmental Tobacco Smoke on Lung Development
Nicotine Exposure During Early Development- effects on the lung
Exposure to Allergens During Development
Development of Atopy in Children
Effects of Air Pollution on Lung Function Development and Asthma Occurence
Environmental Toxicants and Lung Development in Experimental Models
Repair of Environmental Lung Injury During Development
Effects of Aging, Disease and the Environment on the Pulmonary Surfactant System
Environmental Determinants of Lung Aging