The Melanocortin Receptors by Roger D. ConeThe Melanocortin Receptors by Roger D. Cone

The Melanocortin Receptors

EditorRoger D. Cone

Paperback | December 8, 2010

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Roger Cone and a distinguished team of expert investigators provide the first major treatment of this critically important receptor family. The book illuminates the structure and function of these receptors through a wide-ranging review of the latest findings concerning the biology, physiology, and pharmacology of their peptide ligands and covers the major melanocortin peptides, Melanocortin-1-Receptors through Melanocortin-5-Receptors. Topics include the characterization of the melanocortin receptors, the biochemical mechanism of receptor action, and receptor function and regulation. Timely and authoritative, The Melanocortin Receptors offers an up-to-date knowledge base on the remarkably complex structure and functions of the melanocortins, a guide that will prove invaluable for today's neuroscientists, endocrinologists, pharmacologists, and other clinical and experimental investigators working in this fast moving field.
Title:The Melanocortin ReceptorsFormat:PaperbackDimensions:561 pagesPublished:December 8, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617370827

ISBN - 13:9781617370823

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Table of Contents

Part I: Historical Perspectives. Proopiomelanocortin and the Melanocortin Peptides, A. N. Eberle. Melanocortins and Pigmentation, A. B. Lerner. Melanocortins and Adrenocortical Function, M. Bégeot and J. M. Saez. Effects of Melanocortins in the Nervous System, R. A. H. Adan. Peripheral Effects of Melanocortins, B. A. Boston. Part II. Characterization of the Melanocortin Receptors. Melanocortin Receptor Expression and Function in the Nervous System, J. B. Tatro. Cloning of the Melanocortin Receptors, K. G. Mountjoy. Part III. Biochemical Mechanism of Receptor Action. The Molecular Pharmacology of Alpha-Melanocyte Stimulating Hormone: Structure-Activity Relationships for Melanotropins at Melanocortin Receptors, V. J. Hruby and G. Han. In Vitro Mutagenesis Studies of Melanocortin Receptor Coupling and Ligand Binding, C. Haskell-Luevano. Part IV. Receptor Function. The Melanocortin-1 Receptor, D. Lu, C. Haskell-Luevano, D. I. Vage, and R. D. Cone. The Human Melanocortin-1 Receptor, E. Healy, M. Birch-Machin, and J. L. Rees. The Melanocortin-2 Receptor in Normal Adrenocortical Function and Familial Adrenocorticotropic Hormone Resistance, A. J. L. Clark. The Melanocortin-3 Receptor, R. A. Kesterson. The Melanocortin-4 Receptor, R. D. Cone. The Melanocortin-5 Receptor, W. Chen. Part V. Receptor Regulation. Regulation of the Melanocortin Receptors by Agouti, W. O. Wilkison. Melanocortins and Melanoma, A. N. Eberle, S. Froidevaux, and W. Siegrist. Regulation of the Mouse and Human Melanocortin-1 Receptor, Z. Abdel-Malek. Part VI. Future Vistas. Future Vistas. R. D. Cone. Index.

Editorial Reviews

"New data on melanocortin receptors 1-5 and their regulation are the topic of several chapters. A complete, well referenced text of interest to all endocrinologists, neuroscientists, geneticists, physiologists and pharmacologists." - Journal of Pediatric Endocrinology & Metabolism