The Molecular Biology Of Arrestins

Hardcover | June 24, 2013

byLouis M. LuttrellEditorLouis M. Luttrell

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This special volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of arrestins, with contributions from leaders in the field. Arrestins have emerged as central players in the regulation of many facets of G protein-coupled receptor signaling. This volume covers a variety of topics with reviews written by experts in the field. Contributions from leading authorities Informs and updates on all the latest developments in the field

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This special volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of arrestins, with contributions from leaders in the field. Arrestins have emerged as central players in the regulation of many facets of G protein-coupled receptor signaling. This volume covers a variety of topics with revie...

Format:HardcoverDimensions:536 pages, 9 × 6 × 0.98 inPublished:June 24, 2013Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123944406

ISBN - 13:9780123944405

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Table of Contents

Part I: Perspective - The Duality of Arrestin Function

1. Arrestins Come of Age: A Personal Historical Perspective

Part II: The Molecular Biology of Arrestins

    2. True Arrestins and Arrestin-Fold Proteins: A Structure-Based Appraisal

      3. Structural Determinants of Arrestin Functions

        4. Arrestins: Role in the Desensitization, Sequestration and Vesicular Trafficking of G Protein-Coupled Receptors

          5. Arrestins as Regulators of Kinases and Phosphatases

            6. ß-Arrestins: Modulators of Small GTPase Activation and Function

              7. Arrestins and Protein Ubiquitination

                8. Arrestins in Actin Reorganization and Cell Migration

    Part III: The Physiological Roles of Arrestins

      9. The Role of Arrestins in Development

        10. The Role of Arrestins in Visual and Disease Processes of the Eye

          11. b-Arrestins in the Central Nervous System

            12. Arrestins in the Cardiovascular System

              13. Arrestins in Bone

                14. b-Arrestins in the Immune System

                  15. The Role of b-Arrestins in Cancer

                    16. Arrestins in Metabolic Regulation

      Part IV: The Future - The Potential for Arrestin-based Therapeutics

        17. Systems Analysis of Arrestin Pathway Functions

          18. Arrestin Pathways as Drug Targets

          Editorial Reviews

          PRAISE FOR THE SERIES "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--BRITISH MEDICAL JOURNAL