The Neuron: Cell and Molecular Biology by Irwin B. LevitanThe Neuron: Cell and Molecular Biology by Irwin B. Levitan

The Neuron: Cell and Molecular Biology

byIrwin B. Levitan, Leonard K. Kaczmarek

Hardcover | August 13, 2015

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The Fourth Edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The book begins with properties of the many newly discovered ion channels that have emerged through mapping of the genome. These channels shape the way a single neurongenerates varied patterns of electrical activity. Covered next are the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter hormones at synaptic junctions between neurons. The following section examines the biochemical pathways that are linked to the action ofneurotransmitters and that can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce an undifferentiated cellto become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning andmemory. The book contains scores of color figures and fully updated chapters; online content packaged exclusively with the Fourth Edition includes detailed animations of neural processes, in-depth supplemental reading, and additional full-color figures and tables.
Irwin B. Levitan, Ph.D., is Founding Chair of the Department of Neuroscience at Jefferson Medical College, Thomas Jefferson University. Leonard K. Kaczmarek, Ph.D., is Professor of Pharmacology and Cellular and Molecular Physiology, Yale University School of Medicine.
Title:The Neuron: Cell and Molecular BiologyFormat:HardcoverDimensions:600 pages, 9.25 × 6.5 × 0.98 inPublished:August 13, 2015Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199773890

ISBN - 13:9780199773893

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Table of Contents

Preface to the Fourth EditionI. Introduction1. Signaling in the Brain2. Form and Function in Cells of the BrainII. Electrical Properties of Neurons3. Electrical Signaling in Neurons4. Membrane Ion Channels and Ion Currents5. Ion Channels Are Membrane Proteins6. Ion Channels, Membrane Ion Currents, and the Action Potential7. Diversity in the Structure and Function of Ion ChannelsIII. Intercellular Communication8. Intercellular Communication: How Neurons Communicate: Gap Junctions and Neurosecretion9. Synaptic Release of Neurotransmitters10. Neurotransmitters and Neurohormones11. Receptors and Transduction Mechanisms I: Receptors Coupled Directly to Ion Channels12. Receptors and Transduction Mechanisms II: Indirectly Coupled Receptor/Ion Channel Systems13. Sensory ReceptorsIV. Behavior and Plasticity14. The Birth and Death of a Neuron15. Neuronal Growth and Trophic Factors16. Adhesion Molecules and Axon Pathfinding17. Formation, Maintenance, and Plasticity of Chemical Synapses18. Intrinsic Neuronal Properties, Neural Networks and Behavior19. Learning and Memory

Editorial Reviews

"An outstanding, easily readable, and quite up-to-date overview of fundamental neurobiology." --Canadian Journal of Neurological Sciences