The Parathyroids: Basic and Clinical Concepts

Other | July 21, 2001

byRobert Marcus, John P. Bilezikian, Michael A. Levine...

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Written by world experts, this books follows upon the monumental success of the first edition ofThe Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium,The Parathyroidsoffers an objective and authoritative view on controversial clinical issues in this rapidly changing field. Every medical school library and virtually every major hospital library will need this book as a reference for students and clinicians.

Key Features
* Offers objective and authoritative reviews on controversial clinical issues
* Written by world experts on parathyroid hormone and its disorders
* Superb, state-of-the-art compendium in one convenient volume
* Bridges basic science of parathyroid hormone to major clinical disorders
* Practical information on clinical management of parathyroid hormone disorders

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From the Publisher

Written by world experts, this books follows upon the monumental success of the first edition ofThe Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium,The Parath...

Dr. Michael A. Levine is Chief of Endocrinology and Diabetes and Director of the Center for Bone Health at The Children's Hospital of Philadelphia. Dr. Levine holds the Lester Baker Endowed Chair and is Professor of Pediatrics and Medicine at the University of Pennsylvania Perelman School of Medicine. Dr. Levine's research focuses on t...

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Format:OtherDimensions:881 pages, 1 × 1 × 1 inPublished:July 21, 2001Publisher:Elsevier ScienceLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080525776

ISBN - 13:9780080525778

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Table of Contents

Basic Elements of the Parathyroid System
Embryology, Anatomy, and Pathology
Parathyroid Hormone: Gene Structure, Biosynthesis, Metabolism
Parathyroid Hormone-related Protein: Gene Structure, Biosynthesis, Metabolism
Structure-function Analysis of PTH and PTHRP
Receptors for Parathyroid Hormone and PTHRP: Signaling and Regulation
Nuclear targeting: Signaling for PTHRP
Signal Transduction of PTH and PTHRP
Receptors and Signaling for Calcium Ion
Immunoassays for PTH and PTHRP: Clinical Applications
Physiological Aspects of the Parathyroids
Physiology of Calcium Homeostasis
Anabolic and Catabolic Effects of Parathyroid Hormone on Bone: Interaction with Growth Factors
Cellular Actions of Parathyroid Hormone on Osteoblast and Osteoclast Differentiation
Physiological Actions of PTH and PTHRP I: Skeletal Actions
Physiological Actions of PTH and PTHRP II: Renal Actions
Physiological Actions of PTH and PTHRP III: Chondrocyte, Tooth, and Bone Development
Physiological Actions of PTH and PTHRP IV: Vascular and Cardiovascular, Neurological Actions
Physiological Actions of PTH and PTHRP V: Mammary, Reproductive, Epidermal, and Pancreatic Tissue - PTH and PTHRP as Polyhormones
Clinical Aspects Primary Hyperparathyroidism
Normal and Abnormal Growth of Parathyroid Cells
Molecular Genetics of Primary Hyperparathyroidism
Clinical Presentation of Primary Hyperparathyroidism: US
Clinical Presentation of Primary Hyperparathyroidism: Europe
Clinical Presentation of Primary Hyperparathyroidism: India, Brazil, China
Clinical Course of Primary Hyperparathyroidism
Bone Turnover in Primary Hyperparathyroidism
Cytokines in Primary Hyperparathyroidism
Histomorphometric Analysis of Bone in Primary Hyperparathyroidism
Nephrolithiasis in Primary Hyperparathyroidism
Guidelines for the Medical or Surgical Management of Primary Hyperparathyroidism
Medical Management of Primary Hyperparathyroidism
Preoperative Localization of Parathyroid Tissue in Primary Hyperparathyroidism
Surgical Management of Primary Hyperparathyroidism
Ectopic Locations of Parathyroid Glands
Parathyroid Carcinoma
Acute Primary Hyperparathyroidism
Multiple Endocrine Neoplasia Type I
Multiple Endocrine Neoplasia Type II
Familial Forms of Primary Hyperparathyroidism
Familial Hypocalciuric Hypercalce
Secondary Hyperparathyroidism
Parathyroids in Renal Disease: Pathophysiology
Hyperparathyroidism in Renal Failure: Clinical Features, Diagnosis, and Management
Special Considerations
Evaluation of the Hypercalcemic Patient: Differential Diagnosis
Hypercalce Due to PTHRP
Other Local and Ectopic Secretion Syndromes Associated with Hypercalce
Jansen's Disease
Acute Management of Hypercalce
Primary Hyperparathyroidism and Other Causes of Hypercalce in Children and Adolescents
The Hypoparathyroid States
Hypoparathyroidism in Differential Diagnosis of Hypocalce
Parathyroid Function in Magnesium Deficiency
Molecular Genetics of Hypoparathyroidism
Autoimmune Aspects of Hypoparathyroidism
Pseudohypoparathyroidism: Clinical, Biochemical, and Molecular features
Treatment of Hypoparathyroidism
The Parathyroids in Osteoporosis
Parathyroid Function in the Normal Aging Process
Parathyroid Function and Responsiveness in Osteoporosis
Parathyroid Hormone and Growth Hormone in the Treatment of Osteoporosis