The Pharmacology of Alcohol and Alcohol Dependence

Hardcover | April 30, 1999

EditorHenri Begleiter, Benjamin Kissin

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This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, itfocuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section onneuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive andauthoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.

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This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, itfocuses on the pharmacologic mechanisms und...

Benjamin Kissin is at SUNY Health Science Center at Brooklyn.

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Format:HardcoverDimensions:536 pages, 9.49 × 6.93 × 1.18 inPublished:April 30, 1999Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195100948

ISBN - 13:9780195100945

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Table of Contents

1. B. Kissin and H. Begleiter: The Pharmacology of Alcohol DependenceI. General Pharmacology of Alcohol2. H. Kalant: Pharmacokinetics of Ethanol: Absorption, Distribution and Elimination3. A.I. Cederbaum: Metabolism of Ethanol, Acetaldehyde and Condensation Products4. J.M. Kahanna and A.D. Le: Cross-Tolerance: Theoretical and Experimental IssuesII. Neuropharmacology of Alcohol5 Effects of Alcohol on Overall Brain Metabolism. B.M. Altura, B.T. Altura, A. Zhang and Sam Zakhari: 6. B.M. Altura and B.T. Altura: Effects of Alcohol on Brain Circulation7 Effects of Alcohol on Electrophysiological Activity of the Brain. B. Porjesz and H. Begleiter: 8. I. Maltzman and K. Marinkovic: Alcohol, Alcoholism, and the Autonomic Nervous System: A Critical AccountIII. Neuropharmacology of Physical Dependence, Withdrawal, and Physiological Tolerance9. D.B. Goldstein: Effects of Alcohol on Neuronal Membranes10. N.J. Leidenheimer, J.E. Dildy-Mayfield and R.A, Harris: Effect of Ethanol on Voltage-Gated Ion Channels11. B. Tabakoff and P.L. Hoffman: Effect of Alcohol n Neurotransmitters and their Receptors and Enzymes12. R.A, Deitrich, R. Radcliffe and V.G. Erwin: Pharmacological Effects in the Development of Physiological Tolerance and Physical Dependence13. G.F. Koob and K.T. Britton: Neurobiological Substrates for the Anti-Anxiety Effects of Ethanol

Editorial Reviews

"Set[s] a high standard for thorough scholarly reviews of defined subject areas that will be invaluable for current researchers."--The Annals of Pharmacotherapy