The Proteasomal System in Aging and Disease

Other | October 22, 2012

byTilman Grune, Tilman Grune

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This volume ofProgress in Molecular Biology and Translational Sciencediscusses cutting-edge research of proteasomes and proteasome-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure, function, and regulation of the proteasomal system. The second part describes the role of the proteasome in aging and disease.

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field

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This volume ofProgress in Molecular Biology and Translational Sciencediscusses cutting-edge research of proteasomes and proteasome-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure, function, and regulation of the proteasomal system. The seco...

Format:OtherDimensions:436 pages, 1 × 1 × 1 inPublished:October 22, 2012Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123978653

ISBN - 13:9780123978653

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Table of Contents

  1. Structure of the Proteasome
  2. Tobias Jung and Tilman Grune

  3. Structure and Function of the Ubiquitin-Proteasome System: Modulation of Components
  4. Niki Chondrogianni and Efstathios S. Gonos

  5. Immunoproteasomes: Structure, Function, and Antigen Presentation
  6. Deborah A. Ferrington and Dale S. Gregerson

  7. Interactions of the Proteasomal System with Chaperones - Protein Triage and Protein Quality Control
  8. Marc Kästle and Tilman Grune

  9. Proteasome Inhibitors
  10. Boris Cvek

  11. Degradation of Damaged Proteins - The Main Function of the 20S Proteasome
  12. Andrew. M. Pickering and Kelvin. J. A. Davies

  13. Changes of the Proteasomal System During the Aging Process
  14. Martin A. Baraibarand Bertrand Friguet

  15. Proteasome and Cancer
  16. Betul Catalgol

  17. The Ubiquitin Proteasome System and Cardiovascular Disease.
  18. Saul R. Powell, Joerg Herrmann, Amir Lerman, Cam Patterson, Xuejun Wang

  19. Role of the Ubiquitin-Proteasome in Protein Quality Control and Signaling: Implication in the Pathogenesis of Eye Diseases
  20. Fu Shang and Allen Taylor

  21. Proteasome and Neurodegeneratıve Dıseases

Betul Catalgol and Tilman Grune