The Rational Clinical Examination: Evidence-Based Clinical Diagnosis: Evidence-based Clinical Diagnosis by David L. SimelThe Rational Clinical Examination: Evidence-Based Clinical Diagnosis: Evidence-based Clinical Diagnosis by David L. Simel

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis: Evidence-based Clinical…

byDavid L. Simel, Drummond Rennie

Paperback | September 15, 2008

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The ultimate guide to the evidence-based clinical encounter


"This book is an excellent source of supported evidence that provides useful and clinically relevant information for the busy practitioner, student, resident, or educator who wants to hone skills of physical diagnosis. It provides a tool to improve patient care by using the history and physical examination items that have the most reliability and efficiency."--Annals of Internal Medicine

"There is a great deal to like about this book. It is focused on common clinical dilemmas and is well organized, and most chapters are a quick read....The evidence-based examination techniques put forth by Rational Clinical Examination the sort that can be brought to bear on a daily basis - to save time, increase confidence in medical decisions, and help decrease unnecessary testing for conditions that do not require absolute diagnostic certainty. In the end, the whole of this book is greater than its parts and can serve as a worthy companion to a traditional manual of physical examination."--Baylor University Medical Center (BUMC)Proceedings

5 STAR DOODY'S REVIEW!"Physical diagnosis has been taught to every medical student but this evidence-based approach now shows us why, presenting one of medicine's most basic tenets in a new and challenging light. The format is extraordinary, taking previously published material and updating the pertinent evidence since the initial publication, affirming or questioning or refining the conclusions drawn from the data.

"This is a book for everyone who has studied medicine and found themselves doubting what they have been taught over the years, not that they have been deluded, but that medical traditions have been unquestionably believed because there was no evidence to believe otherwise. The authors have uncovered the truth.

"This extraordinary, one-of-a-kind book is a valuable addition to every medical library."--Doody's Review Service
In the tradition of the famous Users' Guides to the Medical Literature, The JAMA series "The Rational Clinical Examination" was created to bring the principles of evidence-based medicine to the diagnostic process. Featuring specific clinical questions, numerous case examples, and precise summaries of available evidence, the RCE series was an instant hit.

Now for the very first time in book form, completely updated with new literature analyses, here is a uniquely practical, clinically relevant approach to the use of evidence in the content of physical examination. Going far beyond the scope of traditional physical examination texts, this invaluable resource compiles and presents the evidence-based meanings of signs, symptoms, and results from physical examination maneuvers and other diagnostic studies. Page after page, you'll find a focus on actual clinical questions and presentations, making it an incomparably practical resource that you'll turn to again and again.

Importantly, the high-yield content of The Rational Clinical Examination is significantly expanded and updated from the original JAMA articles, much of it published here for the first time. It all adds up to a definitive, ready-to-use clinical exam sourcebook that no student or clinician should be without.

  • All the expert perspectives on the application of evidence-based medicine principles-with all the authority of the pioneering JAMA series, The Rational Clinical Examination Packed with updated, new, and previously unpublished information from the original JAMA articles
  • Standardized template for every issue covered, including: Case Presentation; Why the Issue Is Clinically Important; Research and Statistical Methods Used to Find the Evidence Presented; The Sensitivity and Specificity of Each Key Result; Resolution of the Case Presentation; and the Clinical Bottom Line
  • Completely updated with all-new literature searches and appraisals supplementing each chapter
  • Full-color format with dynamic clinical illustrations and images
  • Real-world focus on a specific clinical question in each chapter, reflecting the way clinicians approach the practice of evidence-based medicine
  • More than 50 complete chapters on common and challenging clinical questions and patient presentations
  • Not-to-be-missed coverage of the principles of evidence-based medicine and physical diagnosis, with the concepts of specificity and sensitivity applied to the patient encounter

    Also available:, a new interactive database for the best practice of evidence based medicine
  • David Simel, MD, MHS, Chief, Medicine Service Durham Veterans Affairs Medical Center Professor of Medicine Duke University School of Medicine Durham, NC Drummond Rennie, MD JAMA Chicago, IL Philip R. Lee Institute for Health Policy Studies University of California, San Francisco San Francis...
    Title:The Rational Clinical Examination: Evidence-Based Clinical Diagnosis: Evidence-based Clinical…Format:PaperbackDimensions:732 pages, 10.8 × 8.5 × 0.96 inPublished:September 15, 2008Publisher:McGraw-Hill EducationLanguage:English

    The following ISBNs are associated with this title:

    ISBN - 10:0071590307

    ISBN - 13:9780071590303


    Table of Contents

    1.A Primer on the Precision and Accuracy of the Clinical Examination
    UPDATE: Primer on Precision and Accuracy
    2.Does This Patient Have Abdominal Aortic Aneurysm?
    UPDATE: Abdominal Aortic Aneurysm
    3.Does This Patient Have Abdominal Bruits Useful in the Evaluation of Hypertension?
    UPDATE: Abdominal Bruits
    4.Does This Patient Have an Alcohol Problem?
    UPDATE: Problem Alcohol Drinking
    5.Does This Adult Patient Have Appendicitis?
    UPDATE: Appendicitis, Adult
    6.Does This Patient Have Ascites?
    UPDATE: Ascites
    7.What Can the Medical History and Physical Examination Tell Us About LowBack Pain?
    UPDATE: Low Back Pain
    8.Does This Patient Have Breast Cancer?
    UPDATE: Breast Cancer
    9.Does This Patient Have a Clinically Important Carotid Bruit?
    UPDATE: Carotid Bruit
    10.Does This Patient Have Carpal Tunnel Syndrome?
    UPDATE: Carpal Tunnel
    11.Does This Patient Have Abnormal Central Venous Pressure?
    UPDATE: Central Venous Pressure
    12.Does This Patient Have Acute Cholecystitis?
    UPDATE: Cholecystitis
    13.Does the Clinical Examination Predict Airflow Limitation?
    UPDATE: Chronic Obstructive Airways Disease
    14.Does This Patient Have Clubbing?
    UPDATE: Clubbing
    15.Is This Patient Taking the Treatment as Prescribed?
    UPDATE: Compliance and Medication Adherence
    16(A).Can the Clinical Examination Diagnose Left-Sided Heart Failure in Adults?
    16(B). Does This Dyspneic Patient in the Emergency Department Have Congestive Heart Failure?
    UPDATE: Congestive Heart Failure
    17.Is This Patient Dead, Vegetative, or Severely Neurologically Impaired? Assessing Outcome for Comatose Survivors of Cardiac Arrest
    UPDATE: Death
    18(A).Does This Patient Have Deep Vein Thrombosis? (1998)
    18(B). Does This Patient Have Deep Vein Thrombosis? (2006)
    UPDATE: Deep Vein Thrombosis
    19.Is This Patient Clinically Depressed?
    UPDATE: Depression
    20.Does This Patient Have a Family History of Cancer?
    UPDATE: Family History of Cancer
    21.Does This Patient Have a Goiter?
    UPDATE: Goiter
    22.Does This Patient Have Hepatomegaly?
    UPDATE: Hepatomegaly

    UPDATE: Hypertension
    24.Is This Adult Patient Hypovolemic?
    UPDATE: Hypovolemia, Adult
    25.Is This Child Dehydrated?
    UPDATE: Hypopvolemia, Child
    26.Does This Patient Have Influenza?
    UPDATE: Influenza
    27.Does This Patient Have a Torn Meniscus or Ligament of the Knee?
    UPDATE: Knee Ligaments and Menisci
    28.Is This Adult Patient Malnourished?
    UPDATE: Malnourishment, Adult
    29.Does This Patient Have a Mole or a Melanoma?
    UPDATE: Melanoma
    30.Does This Adult Patient Have Acute Meningitis?
    UPDATE: Meningitis, Adult
    31.Is This Woman Perimenopoausal?
    UPDATE: Menopause
    32.Does This Patient Have Aortic Regurgitation?
    UPDATE: Murmur, Diastolic
    33.Does This Patient Have an Abnormal Systolic Murmur?
    UPDATE: Murmur, Systolic
    34.Does This Patient Have Myasthenia Gravis?
    UPDATE: Myasthenia Gravis
    35.Is This Patient Having a Myocardial Infarction?
    UPDATE: Myocardial Infarction
    36.Does This Woman Have Osteoporosis?
    UPDATE: Osteoporosis
    37.Does This Child Have Acute Otitis Media?
    UPDATE: Otitis Media, Child
    38.Does This Patient Have Parkinson Disease?
    UPDATE: Parkinsonism
    39.Is This Patient Allergic to Penicillin?
    UPDATE: Penicillin Allergy
    40.Does This Adult Patient Have Community-Acquired Pneumonia?
    UPDATE: Community-Acquired Pneumonia, Adult
    41.Does This Infant Have Pneumonia?
    UPDATE: Pneumonia, Infant and Child
    42.Is This Patient Pregnant?
    UPDATE: Early Pregnancy
    43.Does This Patient Have Pulmonary Embolism?
    UPDATE: Pulmonary Embolism
    44.Does This Patient Have an Instability of the Shoulder or a Labrum Lesion?
    UPDATE: Shoulder Instability
    45.Does This Patient Have Sinusitis?
    UPDATE: Sinusitis
    46.Does This Patient Have Splenomegaly?
    UPDATE: Splenomegaly
    47.Does This Patient Have Strep Throat?
    UPDATE: Streptococcal Pharyngitis
    48.Is This Patient Having a Stroke?
    UPDATE: Stroke
    49.Does This Patient Have Temporal Arteritis?
    UPDATE: Temporal Arteritis
    50.Does This Patient Have an Acute Thoracic Aortic Dissection?
    UPDATE: Thoracic Aortic Dissection
    51.Does This Woman Have an Acute Uncomplicated Urinary Tract Infection?
    UPDATE: Urinary Tract Infection, Women
    52.What is Causing This Patient's Vaginal Symptoms?
    UPDATE: Vaginitis
    53.Does This Dizzy Patient Have a Serious Form of Vertigo?
    UPDATE: Vertigo

    Editorial Reviews

    "The work is truly noble, to get past the ghosts of dogma and look at the evidence objectively. The authors and contributors are veritable experts with a cold eye for objectivity. They have produced an important work....This is a book for everyone who has studied medicine and found themselves doubting what they have been taught over the years, not that they have been deluded, but that medical traditions have been unquestionably believed because there was no evidence to believe otherwise. The authors have uncovered the truth....This extraordinary, one-of-a-kind book is a valuable addition to every medical library. 5 Stars!"--Doody's Review Service