The Vaccine Book

Paperback | July 11, 2016

byBarry R. BloomEditorPaul-henri Lambert

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The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy

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The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduc...

Dr. Bloom is Harvard University's Distinguished Service Professor of the Department of Immunology and Infectious Diseases and Former Dean of the Harvard School of Public Health. He received a bachelor's degree and an honorary Sc.D. from Amherst College, and a Ph.D. from Rockefeller University. He is widely recognized for his work in th...

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Format:PaperbackDimensions:664 pages, 8.75 × 6.35 × 0.68 inPublished:July 11, 2016Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128021748

ISBN - 13:9780128021743

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Table of Contents

Part I: Understanding Vaccine Impact at Population and Individual Levels

Chapter 1: The Impact of Vaccination on the Epidemiology of Infectious Diseases

Chapter 2: How Vaccines Work

Part II: How to Design, Assess and Produce Vaccines

Chapter 3: Vaccine Design in the 21st Century

Chapter 4: Vaccine Adjuvants

Chapter 5: Vaccine Production: Main Steps and Considerations

Chapter 6: How are Vaccines Assessed in Clinical Trials?

Chapter 7: Immunological Correlates of Vaccine-Mediated Protection

Part III: Vaccine Safety

Chapter 8: How Vaccine Safety is Monitored

Chapter 9: Vaccination and Autoimmune Diseases

Part IV: New Vaccination Strategies

Chapter 10: Maternal Immunization: Protecting Vulnerable Populations

Chapter 11: New Challenges for Pertussis Vaccines

Part V: Recently Introduced Vaccines

Chapter 12: Pneumococcus, Pneumococcal Disease, and Prevention

Chapter 13: Human Papillomavirus Vaccines

Chapter 14: Rotavirus Vaccines

Part VI: New Approaches for Needed Vaccines

Chapter 15: Antiviral Vaccines: Challenges and Advances

Chapter 16: New Approaches for Needed Vaccines: Bacteria

Chapter 17: Vaccines Against Parasites

Part VII: Major Global Vaccine Challenges

Chapter 18: Tuberculosis Vaccines

Chapter 19: Major Global Vaccine Challenges: Recent Progress in Malaria Vaccine Development

Chapter 20: AIDS Vaccines

Chapter 21: Influenza Vaccines and Vaccination Strategies

Part VIII: Ethical Considerations

Chapter 22: Ethical Considerations in Vaccine Trials in Resource-Limited Settings

Part IX: Vaccine Economics

Chapter 23: Economic Considerations for the Development of Global Vaccines: a Perspective From the Vaccine Industry

Chapter 24: Introduction of Vaccines Into National Programs

Chapter 25: Transitioning Immunization Into the Health Care System: Strengthening Routine Immunization in India

Part X: Trust in Vaccines

Chapter 26: Vaccine Acceptance

Chapter 27: Trust and Confidence in Vaccines: Tales of Three Vaccines, Lessons for Others

Part XI: Future Challenges

Chapter 28: Vaccines for Emerging Viral Diseases

Chapter 29: Cancer Immunotherapy by Checkpoint Blockade

Chapter 30: Adoptive Cellular Therapy With Synthetic T Cells as an Instant Vaccine for Cancer and Immunity