The Weak Hydrogen Bond: In Structural Chemistry and Biology

Paperback | June 1, 2001

byGAUTAM DESIRAJU, Thomas Steiner

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The weak or non-conventional hydrogen bond has been subject of intense scrutiny over recent years in several fields, in particular in structural chemistry, structural biology, and also in the pharmaceutical sciences. There is today a large body of experimental and theoretical evidenceconfirming that hydrogen bonds like C-H...O, N-H...pi, C-H...pi and even bonds like O-H...metal play distinctive roles in molecular recognition, guiding molecular association, and in determining molecular and supramolecular architectures. The relevant compound classes include organometalliccomplexes, organic and bio-organic systems, and also DNA and proteins. The book provides a comprehensive assessment of this interaction type, and is of interest to all those interested in structural and supramolecular science, including fields as crystal engineering and drug design.

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From the Publisher

The weak or non-conventional hydrogen bond has been subject of intense scrutiny over recent years in several fields, in particular in structural chemistry, structural biology, and also in the pharmaceutical sciences. There is today a large body of experimental and theoretical evidenceconfirming that hydrogen bonds like C-H...O, N-H...p...

Gautam Desiraju is at School of Chemistry, University of Hyderabad, India. Thomas Steiner is at Institut fuer Kristallographie, Freie Universitat Berlin, Germany.

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Format:PaperbackDimensions:480 pages, 9.21 × 6.14 × 1.14 inPublished:June 1, 2001Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198509707

ISBN - 13:9780198509707

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Table of Contents

1. Introduction2. Archetypes of the weak hydrogen bond3. Other weak and non-conventional hydrogen bonds4. The weak hydrogen bond in supramolecular chemistry5. The weak hydrogen bond in biological structures6. ConclusionsAppendix

Editorial Reviews

"This book is an important monograph for those working on the related structural chemistry of the weak hydrogen bond" Molecules