The Zebrafish: Disease Models And Chemical Screens

Hardcover | February 1, 2017

byH. William Detrich, IiiEditorLeonard Zon, Monte Westerfield

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The Zebrafish: Disease Models and Chemical Screens, Fourth Edition, the latest volume in the Methods in Cell Biology series, looks at methods for analyzing genetics, genomics, and transcriptomics of zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, developmental epigenetics, and the zebrafish interactome. Covers sections on model systems and functional studies, imaging-based approaches, and emerging studies Includes chapters written by experts in the field Contains cutting-edge material on the topics discussed

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The Zebrafish: Disease Models and Chemical Screens, Fourth Edition, the latest volume in the Methods in Cell Biology series, looks at methods for analyzing genetics, genomics, and transcriptomics of zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic screens for mutations, gene editing in zebrafish, homologous gene ...

Professor of Biochemistry and Marine Biology at Northeastern University, promoted 1996. Joined Northeastern faculty in 1987. Previously a faculty member in Dept. of Biochemistry at the University of Mississippi Medical Center, 1983-1987.Principal Investigator in the U.S. Antarctic Program since 1984. Twelve field seasons "on the ice" s...
Format:HardcoverDimensions:362 pages, 9.41 × 7.24 × 0.98 inPublished:February 1, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128034734

ISBN - 13:9780128034736

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Table of Contents

1. Analysis of Myelinated Axon Formation in Zebrafish

Sarah C. Petersen and Kelly Monk

2. In vivo Analysis of White Adipose Tissue in Zebrafish

John F. Rawls and James Minchin

3. Innate Immune Cells and Bacterial Infection in Zebrafish

Jonathan Astin and Chris Hall

4. Study of Host-Microbe Interactions in Zebrafish

Karen Guillemin and John F. Rawls

5. Infectious Disease Models in Zebrafish

Carol Kim

6. Tumor - Host Innate Immune Cell Interactions in the Zebrafish

Yi Feng

7. Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells

Thomas Boehm

8. Hematopoietic Stem Cell Development: using the zebrafish to identify extrinsic and intrinsic mechanisms regulating hematopoiesis

Trista E. North

9. Zebrafish as a Model for Hemorrhagic Stroke

Brant M. Weinstein

10. Zebrafish Models of Sarcoma

David Langenau

11. Iron Disorders

Barry H. Paw

12. Regenerative Biology of Zebrafish Tendons

Jenna Galloway

13. A Zebrafish Model for VHL and Hypoxia Signaling

Freek van Eeden

14. Zebrafish Provides a Novel Model for Lymphatic Vascular Research

Stefan Schulte-Merker

15. Small Teleost Fish Provide New Insights into Human Skeletal Diseases

Paul Eckhard Witten

16. Zebrafish Models of Human Vision and Hearing Diseases

Monte Westerfield

17. Zebrafish Muscular Dystrophy Models

Peter Currie and Sharon Amacher

18. Liver Diseases

Wolfram Goessling

19. A Zebrafish Xenograft Model for Studying Human Cancer Stem Cells

Ewa Snaar-Jagalska and Lanpeng Chen

20. Analysis of Microglial Interactions with Brain Tumors in Zebrafish

Dirk Sieger

21. Analysis of Pancreatic Disease in Zebrafish

Mary Kinkel

22. Transplantation in Zebrafish

Leonard I. Zon

23. Chemical Screening in Zebrafish for Novel Biological and Therapeutic Discovery

Leonard I. Zon

24. Intestinal Disorders

Michael Pack

25. Zebrafish Models of Leukemia

Thomas Look