This text presents a concise and thorough introduction to the main concepts and practical applications of thermodynamics and kinetics in materials science. It is designed with two types of uses in mind: firstly for a one or two semester university course for mid- to upper-level undergraduateor first year graduate students in a materials-science-oriented discipline and secondly for individuals who want to study the material on their own. The following major topics are discussed: basic laws of classical and irreversible thermodynamics, phase equilibria, theory of solutions, chemicalreaction thermodynamics and kinetics, surface phenomena, stressed systems, diffusion and statistical thermodynamics. A large number of example problems with detailed solutions are included as well as accompanying computer-based self-tests, consisting of over 400 questions and 2000 answers with hintsfor students. Computer-based laboratories are provided, in which a laboratory problem is posed and the experiment described. The student can "perform" the experiments and change the laboratory conditions to obtain the data required for meeting the laboratory objective. Each "laboratory" is augmentedwith background material to aid analysis of the experimental results.