Tight Junctions

Hardcover | June 9, 2006

EditorLorenza González-Mariscal, Lorenza Gonzlez-Mariscal

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This book provides state-of-the-art insight into Tight Junctions (TJs), the intersection of epithelial and endothelial cells in various tissues. Opening with an analysis of the evolutionary development of a transporting epithelium in early metazoans, the book describes current understanding of TJ structure and function information, including evidence supporting the presence of ion channels within TJs. Also deals with TJs of central nervous system myelin and at the blood brain barrier.

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This book provides state-of-the-art insight into Tight Junctions (TJs), the intersection of epithelial and endothelial cells in various tissues. Opening with an analysis of the evolutionary development of a transporting epithelium in early metazoans, the book describes current understanding of TJ structure and function information, inc...

Format:HardcoverDimensions:235 pages, 9.25 × 6.1 × 0.03 inPublished:June 9, 2006Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0387332014

ISBN - 13:9780387332017

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Table of Contents

The Evolution of Transporting Epithelium Phenotype.- Occludin, a Constituent of Tight Junctions.- Tight Junction Channels.- JAM Family Proteins: Tight Junction Proteins That Belong to the Immunoglobulin Superfamily.- Cingulin, A Cytoskeleton-Associated Protein of the Tight Junction.- ZO Proteins and Tight Junction Assembly.- TJ Proteins That Make Round Trips to the Nucleus.- Tight Junctions and the Regulation of Epithelial Cell Proliferation and Gene Expression.- Tight Junction Proteins and Cancer.- Regulation of Paracellular Transport across Tight Junctions by the Actin Cytoskeleton.- Regulation of Tight Junctions' Functional Integrity: Role of a Urinary Factor, Lipids and Ouabain.- Tight Junctions during Development.- Tight Junctions and the Blood-Brain Barrier.- Tight Junctions in CNS Myelin.- Tight Junction Modulation and Its Relationship to Drug Delivery.- Index.