Tissue-Specific Toxicity: Biochemical Mechanisms

Hardcover | April 16, 1992

byWolfgang DekantEditorH. G. Neumann

not yet rated|write a review
This volume provides an up-to-date review of the molecular mechanisms of toxicity. Individual chapters deal with specific aspects of toxicity problems associated with selected organs. Key Features* Contains a review of contemporary knowledge of the molecular mechanisms of toxicity as applied to various organs* Contrasts with other volumes in dealing with the mechanistic approach to the subject* Discusses selected organs in separate chapters

Pricing and Purchase Info

$418.95 online
$427.95 list price
In stock online
Ships free on orders over $25

From the Publisher

This volume provides an up-to-date review of the molecular mechanisms of toxicity. Individual chapters deal with specific aspects of toxicity problems associated with selected organs. Key Features* Contains a review of contemporary knowledge of the molecular mechanisms of toxicity as applied to various organs* Contrasts with other volu...

From the Jacket

Tissue-specific toxicity can involve target-organ-specific metabolism, accumulation of xenobiotics, and tartet-organ-specific responses to insults.In recent years, there has been a tendency to specialise in certain areas, such as liver enzyme bioactivation. This volume brings together contributions reviewing widely differing fields of ...

Format:HardcoverDimensions:263 pages, 9 × 6 × 0.98 inPublished:April 16, 1992Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0122088603

ISBN - 13:9780122088605

Look for similar items by category:

Customer Reviews of Tissue-Specific Toxicity: Biochemical Mechanisms

Reviews

Extra Content

Table of Contents

D.J. McConkey, T.Y. Aw, and S. Orrenius, Role of the Ca2+-Mediated Endonuclease Activation in Chemical Toxicity. W.N. Aldridge, Selective Neurotoxicity: Problems in Establishing the Relevance of in Vitro data to the in Vivo Situation. J.E. Casida and R.F. Toia, Organophosphorous Pesticides: Their Target Diversities and Bioactivation. U. Andrae and H. Greim, Initiation and Promotion in Thyroid Carcinogenesis. W. Bursch, L. Fesus, and R. Schulte-Hermann, Apoptosis ('Programmed' Cell Death) and its Relevance in Liver Injury and Carcinogenesis. P. Steinberg and F. Oesch, Liver Cell Specific Toxicity of Xenobiotics. H.-G. Neumann, S. Ambs, and W. Hillesheim, The Biochemical Basis of Hepatotoxicity. W. DeKant, S. Vamvakas, and M.W. Anders, The Kidney as a Target Organ for Xenobiotics Bioactivated by Glutathione Conjugation. G.S. Yost, Bioactivation and Selectivity of Pneumotoxic Chemicals. M.E. Scheulen and H. Kappus, Anthracycines as Model Compounds for Cardiac Toxicity. Index.

Editorial Reviews

"It is a fitting tribute to a man who spent much of his research career establishing the role of chemical specificity in toxicity."
--ATLA