Triumph of the Heart: The Story of Statins

Hardcover | April 17, 2009

byJie Jack Li

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Over 25 million people in the U.S. alone have benefited from statins - such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines - in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugscome into being? In Triumph of the Heart, Dr. Jie Jack Li, a medicinal chemist and expert on drug discovery, tells for the first time the fascinating story of statins. Drawn from discussions with many scientists involved in the discovery and development of these drugs, the book illuminates the humanside of science by revealing the role played by persistence, luck, and sudden insight that characterize major discoveries. For scientists in the drug industry, health care professionals, students of medicine, and all those intrigued by the basic human drive to explore and discover, Triumph of theHeart offers a compelling view of one of the most important drug discoveries of our time.

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Over 25 million people in the U.S. alone have benefited from statins - such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines - in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugscome into being? In Triumph of the Heart, Dr. J...

Jie Jack Li currently works at Bristol-Myers Squibb Company. He was previously a medicinal chemist Parke-Davis Pharmaceuticals (which was bought in 2000 and closed in 2007 by Pfizer), the birth place of Lipitor. He is the author of Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use (OUP 2006). He lives in Con...

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Format:HardcoverDimensions:224 pages, 6.1 × 9.29 × 0.98 inPublished:April 17, 2009Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195323572

ISBN - 13:9780195323573

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Table of Contents

Prologue1. Cholesterol2. Genesis of Statins3. Merck's Triumph4. Discovery of Lipitor5. Development of Lipitor6. To Market, To Market7. Baycol, Crestor, and Drugs beyond Statins8. ReflectionsAppendixTrademarks of the DrugsBibliography and NotesIndex