TRP Channels in Drug Discovery: Volume I by Arpad SzallasiTRP Channels in Drug Discovery: Volume I by Arpad Szallasi

TRP Channels in Drug Discovery: Volume I

EditorArpad Szallasi, Tamás Bíró

Hardcover | September 20, 2012

Pricing and Purchase Info

$248.48 online 
$271.95 list price save 8%
Earn 1242 plum® points

In stock online

Ships free on orders over $25

Not available in stores

about

Recent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention.  TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date reviews and protocols on the subject, coming from top experts in the field.  Volume I presents a series of state-of-the-art minireviews on the most interesting TRP channels (from TRPA1 to TRPV4), as well as TRP-related protocols involving airways and the genitourinary tract.  Written for the Methods in Pharmacology and ToxicologyT series, this work includes the kind of detailed description and key implementation advice that ensures successful results in the lab. Comprehensive and cutting-edge, TRP Channels in Drug Discovery serves as an ideal reference for graduate students in academic laboratories as well as for pharmaceutical scientists developing new drugs and clinicians interested in novel drugs in the pipeline.
Title:TRP Channels in Drug Discovery: Volume IFormat:HardcoverDimensions:460 pages, 10 × 7.01 × 0.09 inPublished:September 20, 2012Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:162703076X

ISBN - 13:9781627030762

Look for similar items by category:

Customer Reviews of TRP Channels in Drug Discovery: Volume I

Reviews

Table of Contents

Part I: Introduction 1. Introduction to TRPs: A Quest for Novel Drug Targets            Bernd Nilius 2. TRP-Mediated Cytoskeletal Reorganization: Implications for Disease and Drug Development            Chandan Goswami Part II: TRP Channels, from A1 to V4 3. TRPA1 in Drug Discovery            Jun Chen, Steve McGaraughty, and Philip R. Kym 4. Canonical Transient Receptor Potential Channel (TRPC) Expression, Regulation, and Function in Vascular and Airway Diseases            Brij B. Singh, Christina M. Pabelick, and Y.S. Prakash 5. TRPM2 Function and Potential as a Drug Target            Barbara A. Miller 6. The Ca2+-Activated Monovalent Cation Selective Channels TRPM4 and TRPM5            Colsoul Barbara, Kecskes Miklos, Philippaert Koenraad, Menigoz Aurelie, and Vennekens Rudi 7. The Emerging Role of TRPM7 in the Regulation of Magnesium Homeostasis            Vladimir Chubanov, Jonathan T. Eggenschwiler, Thomas Gudermann, and Alexey G. Ryazanov 8. TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation            David D. McKemy 9. TRPML Channels in Function, Disease, and Prospective Therapies            David A. Zeevi 10. The TRPP Signalling Module: TRPP2/Polycystin 1 and TRPP2/PKD1L1            Alexis Hofherr 11. TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities            Olivier Radresa, Stephen Zicha, William Brown, and Jennifer M.A. Laird 12. Nociceptive and Non-Nociceptive Roles of TRPV3 and Its "Druggability"            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Alexis Hofherr 11. TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities            Olivier Radresa, Stephen Zicha, William Brown, and Jennifer M.A. Laird 12. Nociceptive and Non-Nociceptive Roles of TRPV3 and Its "Druggability"            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Olivier Radresa, Stephen Zicha, William Brown, and Jennifer M.A. Laird 12. Nociceptive and Non-Nociceptive Roles of TRPV3 and Its "Druggability"            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson