TT Viruses: The Still Elusive Human Pathogens by Ethel-Michele de VilliersTT Viruses: The Still Elusive Human Pathogens by Ethel-Michele de Villiers

TT Viruses: The Still Elusive Human Pathogens

EditorEthel-Michele de Villiers, Harald zur Hausen

Hardcover | December 3, 2008

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Eleven years ago the circular DNA of a novel single-stranded virus has been cloned and partially characterized by Nishizawa and Okamoto and their colleagues. According to the initials of the patient from whom the isolate originated, the virus was named TT virus. This name has been subsequently changed by the International Committee on Taxonomy of Viruses (ICTV) into Torque teno virus, permitting the further use of the abbreviation TTV. Although initially suspected to play a role in non A -E hepatitis, subsequent studies failed to support this notion.Within a remarkably short period of time it became clear that TT viruses are widely spread globally, infect a large proportion of all human populations studied thus far and represent an extremely heterogeneous group of viruses, now labelled as Anelloviruses. TT virus-like infections have also been noted in various animal species. The classification of this virus group turns out to be difficult, their DNA contains between 2200 and 3800 nucleotides, related so-called TT-mini-viruses and a substantial proportion of intragenomic recombinants further complicate attempts to combine these viruses into a unifying phylogenetic concept.
Title:TT Viruses: The Still Elusive Human PathogensFormat:HardcoverDimensions:243 pages, 9.25 × 6.1 × 0.03 inPublished:December 3, 2008Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540709711

ISBN - 13:9783540709718

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Table of Contents

Preface.- History of discoveries and pathogenicity of TT viruses.- Classification of TTV and related viruses (anelloviruses).- TT viruses in animals.- Replication of a protein synthesis by TT viruses.- Immunobiology of the Torque Teno viruses and other anelloviruses.- Intragenomic rearrangement in TT viruses - a possible role in the pathogenesis of disease.- TT viruses - with oncogenic or tumorsuppressive properties?.- Relationship of Torque Teno viruses to chicken anemia virus.- Apoptosis inducing proteins in chicken anemia virus and TT virus.- Chicken anemia virus.- Subject index