Tuberous Sclerosis Complex by Manuel Rodriguez GomezTuberous Sclerosis Complex by Manuel Rodriguez Gomez

Tuberous Sclerosis Complex

EditorManuel Rodriguez Gomez, Julian R. Sampson, Vicky Holets Whittemore

Hardcover | July 29, 1999

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Tuberous Sclerosis is a genetic disease characterized by lesions of the skin and central nervous system, seizures, and sometimes sever mental retardation. Infants with this disease may appear overactive, autistic, or socially impaired. Because tuberous sclerosis involves abnormal cellulardifferentiation, aberrant neuronal migration, and excessive cell proliferation, this thoroughly revised edition will be of interest to a wide range of professionals involved in the study of biological mechanisms underlying many genetically determined neurological disorders.

About The Author

Manuel R. Gomez is at Mayo Medical School (Emeritus). Julian R. Sampson is at University of Wales College of Medicine.

Details & Specs

Title:Tuberous Sclerosis ComplexFormat:HardcoverPublished:July 29, 1999Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195122100

ISBN - 13:9780195122107

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Table of Contents

Preface. 1. History2. Criteria for Diagnosis3. Population Studies4. Natural History of Cerebral TSC5. Psychiatric Features6. Electroencephlography7. Magnetoencephalography8. Central Nervous System Imaging9. Neuropathology10. Ophthalmic Findings11. Dermatologic Manifestations12. Renal Involvement13. Cardiac Manifestations14. Pulmonary Manifestations15. The Endocrine System16. Liver, Dig Tract, Spleen, Arteries, Lymph17. Imaging of Bone and Great Vessels18. Lineagages of Cells in the CNS19. Gene Mapping: TSC120. Mapping of TSC2: Tuberin21. Genetic Couselling22. Impact of Diagnosis on Patient and Family