Tumor Necrosis Factor: Methods and Protocols by Angelo CortiTumor Necrosis Factor: Methods and Protocols by Angelo Corti

Tumor Necrosis Factor: Methods and Protocols

EditorAngelo Corti, Pietro Ghezzi

Paperback | November 10, 2010

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A comprehensive collection of readily reproducible techniques for TNF production, characterization, mutagenesis, and detection in biological specimens. Also included are several in vitro assays and animal models for studying the role of TNF in various TNF-related diseases and in cancer. The collection offers molecular and cellular biologists, pharmacologists, and toxicologists a diverse set of versatile, cutting-edge tools for illuminating the pathophysiological roles of TNF in disease and for identifying new drugs.
Title:Tumor Necrosis Factor: Methods and ProtocolsFormat:PaperbackDimensions:292 pages, 9.02 × 5.98 × 0.07 inPublished:November 10, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617374326

ISBN - 13:9781617374326

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Table of Contents

Tumor Necrosis Factor as a Pharmacological TargetPietro Ghezzi and Anthony CeramiProduction and Characterization of Recombinant Human and Murine TNFFlavio Curnis and Angelo CortiPurification of TNF Binding ProteinsHartmut Engelmann, Dani Aderka, and David WallachProduction and Characterization of Receptor-Specific TNF MuteinsPaul Ameloot and Peter BrouckaertTNFa Promoter PolymorphysmsSilvia Fargion, Luca Valenti, Paola Dongiovanni, and Anna Ludovica FracanzaniDetection of TNF and TNF Receptor mRNA in Cells and TissuesRoberto Furlan, Giuliana Salani, Alessandra Bergami, and Gianvito MartinoImmunohistochemical Localization of TNFa and Its Receptors in the Rodent Central Nervous SystemPaolo Bigini and Tiziana MenniniTNF Signaling: Key ProtocolsMarta Muzio and Simona SaccaniMore Than One Way to Die: Methods to Determine TNF-Induced Apoptosis and NecrosisTom Vanden Berghe, Geertrui Denecker, Greet Brouckaert, Dmitri Vadimovisch Krysko, Katharina D'Herde, and Peter VandenabeeleAssessment of TNFa-Induced Endothelial Damage Through the Loss of Its Barrier FunctionElisabetta FerreroGenetic Engineering in the Mouse: Tuning TNF/TNFR ExpressionEleni Douni, Maria Alexiou, and George KolliasTNFa in Experimental Diseases of the CNSRoberto Furlan, Pia Villa, Giorgio Senaldi, and Gianvito MartinoIn Vivo Vascular Leakage AssayMaria Elena FerreroAnimal Models of Endotoxic ShockPia Villa and Pietro GhezziCollagen-Induced Arthritis as a Model for Rheumatoid ArthritisRichard O. WilliamsMyocardial Infarction: Animal ModelsStefano Chimenti, Eleonora Carlo, Serge Masson, Antonio Bai, and Roberto LatiniTumor Vascular Therapy With TNF: Critical Review on Animal ModelsTimo L. M. ten Hagen and Alexander M. M. EggermontStrategies for Improving the Anti-Neoplastic Activity of TNF by Tumor TargetingAngelo CortiIndex

Editorial Reviews

"...offers molecular and cellular biologists, pharmacologists, and toxicologists a diverse set of productive, cutting-edge tools for illuminating pathophysiological roles of TNF in disease and for identifying new drugs." - Tumori